I have a middle ear infection and was first prescibed the amoxicillin, after the 3rd or 4th day my ear plugged up again. I went back to ready care and that doctor prescribed the cefdinir. Is it safe to take both of these antibiotics at the same time. Cefdinir is 300 mg every 12 hours and the Amoxicillin-clavulanate 875-125 mg is also every 12 hours. He didn't say stop the amoxicillin.