I took vitamin D3 for 2 weeks, but after just a few days, I started to experience depression and by the end of the two weeks, I was having suicidal thoughts - I took 1000 units per day with a meal - also, the metallic taste was unbearable - other meds I take daily are Hydrochlorothiazide - 25mg, regular aspirin, and atenolol 25mg - I stopped taking Vit. D3 on Aug. 28 - in a few days my metallic taste was gone and my depression disappeared.