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Why do they say to avoid grapefruit when taking Crestor 20MG?

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Inactive 5 Dec 2012

Hello TLV2,

According to the Crestor brand (rosuvastatin) package insert, the use of grapefruit is not a restriction when taking rosuvastatin.

I also and called the manufacturer and read the customer leaflet (I do not take the med, someone close to me does) ran an interaction check, Crestor interacts with other medication, but no interaction with grapefruit.

What should I avoid while taking Crestor?

Avoid using antacids without your doctor's advice. Use only the type of antacid your doctor recommends, and do not take it within 2 hours after taking Crestor. Some antacids can make it harder for your body to absorb Crestor.

Avoid eating foods that are high in fat or cholesterol. Crestor will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Read more at: https://www.drugs.com/crestor.html

There is only ineteractions with other medications only, not with food, specially nothing about grapefruit, click on the link please:

https://www.drugs.com/drug-interactions/rosuvastatin,crestor.html

I have the patient leaflet of Crestor in my hands from AstraZeneca, and grapefruit is no mentioned at all.

I called them for your peace of mind, and spoke to a nurse , she said it is ok to have grapefruit.

AstraZeneca Pharmaceuticals,
1800 Concord Pike
P.O. Box 15437
Wilmington, DE 19850-5437
Contact Details
Phone: (800) 236-9933
Website:www.astrazeneca-us.com

Take care,

maso.-

Votes: +0
kaismama 5 Dec 2012

Way to go sunshine... other statins grapefruit effects however.

Inactive 5 Dec 2012

Thanks Kaismama, hope you are well.

StevenBenn 8 Aug 2017


I take Rosuvastatin and really like grapefruit especially ruby red grapefruit juice but haven't had any in years. I use to take metatopoparol and was recently taken off of it. I could not recall which of the two had a caution label warning not to eat grapefruit if taking. Therefore, I went to CVS and spoke with the pharmacist. She said, "You should not consume grapefruit if taking a statin ". Since I was headed to the market with hopes of coming home with some grapefruit when I stopped by the neighboring pharmacy, I was a bit saddened to hear what she had to say.

StevenBenn 8 Aug 2017


I take Rosuvastatin and really like grapefruit especially ruby red grapefruit juice but haven't had any in years. I use to take metatopoparol and was recently taken off of it. I could not recall which of the two had a caution label warning not to eat grapefruit if taking. Therefore, I went to CVS and spoke with the pharmacist. She said, "You should not consume grapefruit if taking a statin ". Since I was headed to the market with hopes of coming home with some grapefruit when I stopped by the neighboring pharmacy, I was a bit saddened to hear what she had to say.

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