I was put on Effexor Extended Release (75mg) about a month ago. I was coming off of Seroquel when they changed my diagnosis from Borderline Personality Disorder to generalized depression, social phobia, and PTSD. They also put me on Clonidine (0.2 - 0.3 mg), but I don't notice any change in my sex drive when I take it. It just makes me tired. I notice after a few hours of taking my Effexor that I get a ridiculous sex drive (needed details: I'm a 30 year old female). I'm not sure if it's just me hitting my 30s and having the increased sex drive that comes with it, or if it's actually the Effexor. I thought that anti-depressants were supposed to put a damper on sex lives, not make it almost uncontrollable.