Has anyone experience increased anxiety after taking b12 5000 supplement ?

This helps me feel better as I experience a great deal of depression not long after taking B12 liquid sublingual drops. I thought I’d lose my mind! Last spring I was finally able to wean off of Xanax, which no doctors told me was habit forming! What a relief but I began to wonder if I made a mistake after this terrible depression and anxiety hit after B12. Since I have the MTHFR genetic factor I do not convert folic acid properly which is necessary for B12 to absorb and work correctly. This is a struggle that may contribute to many people taking too much B12 or the wrong type. I’m still researching but wondered if anyone else was hurting like this?

As a Vegan for three years now, I have had to take Vit B12. I have read Dr. Michael Greger’s books and receive his Nutrition Facts.org. Research messages on my emails. After having blood work done, I found that the recommended 1,000mcg/day is sufficient. That is also recommended for my age group. Check out some well know sources, as Vegans must supplement with it. No need to overload if not necessary.

Late response but the same here. I started taking the 5000 mcg lozenge of B12 about 10 days ago. Had the same result. Thanks for posting. In my search for that dosage, all I found was yes it's safe. I beg to differ. Same result with the shot but the lozenge was even worse.

"Vitamin B12
Most people associate B12 with health, energy, and vitality, so it's another vitamin found in high concentrations in many energy formulas. Like B6, high doses of B12 (>1,000 mcg) increase neurotransmitter levels, and as a result, have stimulating properties. This can be beneficial for people experiencing mood disorders like depression, ***though it can sometimes result in an "overshoot" and cause restlessness, anxiety, worry, and difficulty sleeping***.

For most people, this isn't a supplement you need to take every day unless you have a diagnosed deficiency or are using it therapeutically for chronic fatigue or another condition."

I was told I was low on vitamin b12 and was to get 5 injections After first one I was perfect Got second the following week and had diarrhoea and couldn’t eat Went back to Doctor and he said he thought nothing to do with b12 injections and gave me another one Thst was four weeks ago and I have terrible anxiety and do not want to touch food I’m hoping it will pass It is the worse experience of my life

Yes I have. With out a doubt. I have had B12 in various mulitvitamins on an off over a period of a couple of years until I realised it was the B12 that was doing me harm.

I have then a year or so later taken other supplements and was unwell with them bc they had B12. If I take any other types of herbs and supplements that don't have B12 but with other vitamins, I am fine. So I generally try to get vitamins without B12.

I just did it again accidentally and the same thing happened after a couple of days. Which is what led me to your blog.

Having excess B12 may not be good for everyone. It certainly isnt good for me.

Stay attuned to your body and stop any vitamins if you feel worse. And figure out which one is the culprit.

Hello... I know this is an older thread, but I wanted to see if anyone found alternatives? I eat plant-based, and I know that I am on the low side with vitamin B12, but even the smallest dose makes my anxiety attacks so much worse. My heart races, and I feel lightheaded, etc. My plant based physician said that our bodies only need 2.4 mcg of B12 per day. The supplements at 1,000 mcg or 5,000 mcg are like 16,000% of the daily requirements (seriously, look on the back of the bottle). So I have a chewable vitamin B12 tablet, and I bite off the tiniest amount every day, like so small otherwise it will exacerbate my panic attacks. I have tried all of the different types too, and they all do the same thing :(

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Featured snippet from the web
The typical general supplemental dose of vitamin B12 is 1-25 mcg per day: The recommended dietary allowances (RDAs) of vitamin B12 are: 1.8 mcg; older children and adults, 2.4 mcg

Omg this post is from 2016 but still SO IMPORTANT in almost 2020. Thank you so much for sharing, it helped me understand I wasn't having a crazy anxiety attack out of the blue. I took one 2,500mcg b12 and it drove me completely nuts! I usually have anxiety and take prozac for it, but it's never this bad. Who knew too much B12 could have so much impact?? Again, thank you for making everything clearer for me!

I’ve been having anxiety as well after taking liquid b 12, I diluted the dose down to 125MCG’s and it’s still making me anxious. I’m gonna keep trying because my level is so low, and I’m having tingling in my arms, legs, hands, and feet.

Hello everyone! I have increased anxiety too since I took B12, can anyone update how they are feeling after they stopped taking it? Do you guys feel better? Thank you so much for your answer!

Good Morning,
I have been taking a B-12 1000mcg Tablet supplement for months and I've been fine. But recently we moved and I felt a bit more sluggish, so I purchased a B-12 5000mcg liquid sublingual. I've been taking it for over a week and I have been so overwhelmed with nothing but anxiety symptoms and mood swings. It was terrible, I too felt like I was crawling out of my skin. I couldn't understand why the sudden change, I had bad anxiety up to about 5 years ago and had to control it with Xanax for Years. I thought I was going to have to start again. I woke up this morning thinking, Is it the high dose of B-12? And thank God I found this, I now know I'm not alone. I'll wait a few days and go back to my 1000mcg tablet.
Thank You Everyone.

Hello. My mom told me (I’m a 45 year old
Woman and mom) to take Methyl B12 for energy. It did give me energy and I stopped taking naps but it turned me into a raving lunatic! I have no idea why. Mine were the lozenges you let dissolve on the tongue. My mom said I was taking too much (5000 iu) so I just bit the lozenge in 1/2. I’m still a lunatic screaming at everyone. I stopped it. I’m back to normal.

1) Vitamin D3 should be taken with Vitamin K2 (check out Dr. Kate Rheaume-Bleue and the Calcium Paradox box) - from what I understand D3 alone could contribute to arterial stiffness or worse.
2) Consumption of Green Tea inhibits absorption of folates from food due to high content of catechins. Since I also drink a lot of milk (which increases intestinal absoprtion of catechins) this means my folate absorption is low.
3) Taking B12 might affect the ability to absorb Folates. Earlier last year I was supplementing B12 (methlycobalmin - 1000ug) and got progressively more and more anxious to the point where I had to stop them. Lately I did some blood results which show that whilst my B12 levels are good, my folates are low.

My suspicion is that B12 affects folates absorption especially when this is accompanied with the intake of Green Tea ( I am a heavy green tea drinker).