I have been taking Seroquel for a long time, lately when I take my usual dose at night of 200mg at night i feel weird things like I can't be still, my legs feel all kind of adrenaline sensation, and I cannot lay still. It's a horrible sensation and the only relief I can get from it is to keep jumping about until the sensation goes away this can take up to 2 hours ...
Has anyone else ever had this happen ? What may be causing this ? Is it the Seroquel ??
Oh and BTW I have experienced weightless over a time, yes my anxiety was very bad initially but over a period of about 5 years I have lost approximately 10 to 15kgs, I know if it was the Seroquel that actually did this, but I think it was more that the drug made me feel alot better hence the weight loss. I know of people whom have gained weight- yes - but this should not be a deciding factor as to whether or not it could work for you. How you feel will affect how you look ... not the other way around !!
Agitation in my leg muscles and body after taking my dose of Seroquel?
Question posted by Debsta on 28 Aug 2021
Last updated on 28 August 2023 by alcon1502
4 Answers
I’m been 50 mg quetiapine for last 20 years. It is good for sleeping. I have no need to upper dose. quetiapine is a very strong medication. I’m curious why patients go to higher doses. You should talk your doctor about your complaints. Good luck
I have taken Quetiapine (generic Seroquel) since 2014. My current dose is 200mg at bedtime and 50mg once in the daytime. There was a period of time in the first 5 years that I would have agitated leg syndrome. It only affected one leg. It was annoying and would cut into my sleep time. I tried to figure out a way of stopping the feeling of agitation. I worked on it for awhile. The solution was to somehow have the other (non-agitated) leg hold the agitated leg to prevent the movement of the agitated leg.
To clarify, I have a tremor in my left hand. So that I don't go nuts having the tremor bother me while sleeping, I will pin the tremor hand underneath my other hand. The tremor can't present itself because the hand is being held down by the other hand.
Let's apply this principle to the leg agitation situation. I tuck the agitated leg under the other non-agitated leg and use that other leg to prevent the agitated leg from moving. More or less, pinning it down. So, now the agitated leg cant move. Its the movement of the leg that is bothersome.
For the longest time, that took care of the agitated leg problem. However, recently it has returned. So its back to pinning one leg over the other. That's the best I can do for you. Over the last 9 years, 95% of the time, quetiapine took care of my sleeping issues. This agitation situation has accounted for 5% of the time.
Hi, Debsta!
It does sound very much like Restless Leg Syndrome (RLS) and it affects about 1-10% of Seroquel users as well as other antipsychotic medications... not that it helps you to know that.
Have you spoken to your doctor about this? Since you do well on it and don't seem to want to stop it you should talk with your doctor about some options. There are several medications which raise dopamine levels in the brain that have been shown to be very effective in many cases.
BTW, thanks for the comment on weight. Yes, I've gained some weight and it could be caused by any one or the combinations of meds I take. Without these medications I would most surely be back in the hospital and so I've gotten my head around it and have found that it no longer affects my self image. Mental health comes first and foremost for me.
Best regards and I hope you can find some help quickly.
Yeah I pleased to hear that you have put yourself and your mental health first. It's really important that you are. Sure you might gain some weight or lose some ... really does it matter that much, learn to like yourself, for what is within you, how much better you're feeling now rather than ending up in hospital again. You gotta weigh that up.
We are programmed so much by self image, but when is the last time you saw some one who has it all - good looks, a so called perfect body transformed by plastic surgery or other means - really happy ?? They look unhappy to me at least. When is the last time you saw an animal reject a same (sometimes different) species just because they were slightly different ?? As humans we have a lot to learn yes
Yes, I got restless leg syndrome if I hadn’t fallen asleep within 30 minutes of taking the Seroquel generic, Quetiapine. In addition, after the 30 minutes, my nasal passages would swell shut. Perhaps, a different company manufactured your SEROQUEL, which, if a little different, could have caused the new symptoms. My heart goes out to you, I suffered through hours and hours of fighting side effects and losing sleep, as you are. Drinking sour pickle juice helped the RLS, sometimes. I had to stop taking it altogether. Now, I depend on Diazepam and nighttime sinus medicine to get my sleep. The main reason I took SEROQUEL was to stop the night terrors; so, they are back. Good luck, I hope you find a solution.
Related topics
adrenalin, seroquel, bipolar disorder, allergic reactions, agitation, dosage, muscle
Further information
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
