I stopped 4 days ago. I feel awful. Any suggestions to help me feel better please?
After finishing Epclusa, I'm having worse side effects from finishing it!
Question posted by Arainia on 9 June 2019
Last updated on 16 August 2021 by Dmbarnes
Did anyone else feel awful with withdrawal or flu like symptoms after completing 12 weeks of Epclusa and how long until you felt better? Can I do something to help with the symptoms? I am really depressed - I ache all over and have nausea.
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Answers
4 days after stopping I started feeling worse than I ever felt when I was taking it. Nausea and brain fog every morning. I am having difficulty completing simple tasks, lack of focus and ability to concentrate. I am taking vitamins, drinking plenty of water, eating healthy, but I feel like total crap. Also my hair is falling out. My doctor said I should feel better after two weeks, which is 2 days from now. I would love to know if anyone else has had this experience and if anything can help me.
Drugs like Epclusa have unpleasant side-effects, including flu-like symptoms. that may erode the quality of life. As published by MayoClinic here are some tips for managing the most common side-effects:
FATIGUE - Feeling tired and run-down is the most common side effect of this type of medication. To avoid fatigue or limit its impact, try:
1. Cutting back on work hours, if possible
2. Napping during the day
3. Taking a walk on most days to increase your alertness and promote better sleep
4. Drinking a caffeinated beverage in the morning
5. Considering antidepressant therapy if depression may be contributing to your fatigue
FLU-LIKE SYMPTOMS- Headache, muscle aches, and fever — are typically accompanied by fatigue. You can cope with these signs and symptoms by:
1. Taking an over-the-counter medication such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others) as needed while the symptoms last — if your doctor says it's safe for you
2. Drinking plenty of fluids
3. Getting enough rest
4. Avoiding strong sunlight and bright indoor lights to prevent headache
5. Using warm, moist heat on achy muscles
LUNG PROBLEMS - Cough is the most common respiratory side effect. Shortness of breath also may develop, as may airway and lung infections. See your doctor if you often feel out of breath or if you have a fever and a deep cough that produces thick sputum. To manage a cough:
1. Drink plenty of fluids throughout the day
2. Use a humidifier
3. Use sugar-free hard candy or cough drops to soothe a scratchy throat
MOOD CHANGES - Hepatitis C treatment may cause depression, mood swings, and confusion. These side effects aren't trivial, particularly for people who have a history of mental health conditions. Strategies for coping with depression include:
1. Taking an antidepressant throughout treatment and for a few months after treatment
2. Avoiding caffeine if you're feeling anxious or irritable
3. Taking regular walks or going to a gym regularly for mild exercise
4. Talking to your doctor or a mental health professional immediately if you feel like you might hurt yourself or someone else
SKIN PROBLEMS - Hepatitis C drugs can sometimes cause dry skin, itching and a rash triggered by sunlight. Hair loss also may occur, but the hair usually grows back after treatment. Protect your skin and hair by:
1. Bathing and showering in warm (not hot) water
2. Applying plenty of moisturizing lotion or cream to your skin after you shower or bathe
3. Putting on sunscreen before going outside
4. Using mild, unscented laundry detergent and avoiding fabric softener
5. Rubbing or pressing on itchy skin instead of scratching
6. Using mild shampoo and gentle styling techniques
7. Switching to a satin pillowcase to reduce friction on your scalp
SLEEP PROBLEMS -Difficulty falling or staying asleep (insomnia) may be a result of mood problems and potentially worsening depression and anxiety. To get enough sleep:
1. If you're also being treated for depression, take an antidepressant that improves sleep rather than one that makes you alert
2. Stick to a regular schedule of going to bed at night and getting up in the morning
3. Avoid reading and watching TV in bed
4. Avoid caffeine
5. Try not to nap during the day
6. Eat a light meal well before bedtime
7. Limit the fluid you drink in the two hours before bedtime, so you won't have to go to the bathroom during the night
8. Wind down with a recorded relaxation exercise, warm bath or massage before going to bed
9. Take diphenhydramine (Benadryl, others) or another sleep-promoting medication under your doctor's supervision
STOMACH PROBLEMS - antivirals can cause nausea, vomiting, diarrhea, appetite loss or a combination of these side effects in some people. Many also complain of a bad taste in the mouth. Sometimes, these side effects can lead to weight loss. Coping strategies include:
1. Eating small meals
2. Eating food cold or at room temperature so its odor is less intense
3. Choosing high-protein snacks, such as cheese or peanut butter, if you can tolerate them
4. Trying protein drinks if solid food is unappealing
5. Avoiding spicy or greasy foods
6. Eating foods that contain soluble fiber, such as bananas, rice, applesauce and white toast, to relieve diarrhea
7. Avoiding dairy products during and for several days after a bout of diarrhea
8. Taking a walk before eating
9. Using plastic utensils if you have a metallic taste in your mouth
Hope this could help you feel better soon!
Related topics
Further information
- Epclusa uses and safety info
- Epclusa prescribing info & package insert (for Health Professionals)
- Side effects of Epclusa (detailed)
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