I took 1 Nexium straight out of the bottle, then filled my pill box with them as well, an hour later i went to take my other medications (which were in the pill box) taking them all at once forgetting that there was an extra Nexium in along with my pills for that day there for taking 2 Nexium's for the day. Therefore making it 44mg for the day and not the directed 22mg from the box. Is this safe?