BoviBlock

Company: VetOne

Non-antibiotic

Dry Cow Intramammary Teat Sealant Device

As an aid in the prevention of new intramammary infections throughout the dry period

Each syringe contains 4g intramammary paste

Containing 65% Bismuth Subnitrate

For use in nonlactating dairy cattle

For animal use only

Read Entire Package Insert Carefully Before Using This Product

BoviBlock™ is a sterile, antibiotic-free, off-white smooth paste. It is presented, ready to use, in syringes, each containing 4 g of intramammary infusion composed of 65% Bismuth Subnitrate, in a mineral oil vehicle. BoviBlock is indicated as an aid in the prevention of new intramammary infection throughout the dry period by providing a malleable barrier in the teat canal. This results in a reduction in the incidence of clinical mastitis in the dry period.

It is recommended that BoviBlock be used as part of a herd approach to dry cow management and mastitis control.

WITHDRAWAL INFORMATION: For use in dry cows only. Zero-day milk and meat withdrawal when used alone.

If BoviBlock is administered following an antibiotic infusion, the withdrawal periods for meat and milk for the antibiotic must be observed.

Precautions

Keep out of reach of children. For animal treatment only. If BoviBlock gets on skin, wash with soap and warm water. If accidentally administered to a lactating cow, product can be stripped out by hand. An SDS may be obtained by calling Norbrook at 1-866-591-5777 or visiting the Norbrook, Inc. website at www.norbrook.com.

Adverse Reactions

Mastitis-causing bacteria introduced into the teat at the time of infusion of BoviBlock have been associated with adverse reactions. Each teat must be cleaned and disinfected prior to infusion of BoviBlock. See below for instructions for administration of infusion products.

Storage

BoviBlock should be stored at room temperature 59°-86°F (15°-30°C). In very cold temperatures BoviBlock may become difficult to administer and should be warmed to room temperature. Individual tubes should not be immersed in water. The BoviBlock bucket can be lowered into a 5 gallon bucket filled with warm water to warm the tubes.

BoviBlock Indications

BoviBlock is intended as an aid in the prevention of new intramammary infections of dairy cattle throughout the dry period.

Dosage and Administration

After last milking at dry-off, clean and disinfect the teats with the alcohol wipes provided. Gently pinch the base of the teat near the udder attachment to close the teat canal. Infuse entire contents of one syringe of BoviBlock into each quarter by inserting the nozzle into the teat and applying gentle continuous pressure to the plunger until the paste is expressed. BoviBlock must remain in the teat canal to be effective.

Do not massage teat or udder following infusion. If an antibiotic is infused into the teat, the teat should be re-wiped with the alcohol wipe provided prior to infusion with BoviBlock. A clean, disinfected and dry teat is essential, as BoviBlock possesses no antimicrobial activity. It is advisable to use an appropriate teat disinfectant following the infusion.

BoviBlock is presented in syringes with a 2-Stage tip. This 2-Stage tip allows for either full or partial insertion into the teat orifice. Partial insertion only is preferable, as it may prevent unnecessary damage to the teat orifice and reduce the risk of infection. Full insertion may be needed for large teat orifices.

Option 1: For short tip intramammary administration