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Can you take an antacid with omeprazole?

Medically reviewed by Carmen Pope, BPharm. Last updated on Oct 16, 2023.

Official answer

by Drugs.com

You can take an antacid with omeprazole if you are still getting symptoms of indigestion because it can take several days for omeprazole to start working. Take omeprazole as directed (usually taken once daily on an empty stomach), and take antacids as needed to relieve indigestion pain after eating. But tell your doctor if several weeks have gone past and omeprazole does not seem to be working or you are still taking antacids.

References
  • Omeprazole (Oral Route) Mayo Clinic. https://www.mayoclinic.org/drugs-supplements/omeprazole-oral-route/proper-use/drg-20066836
  • Omeprazole Oral - Uses, Side Effects, and More Web MD. https://www.webmd.com/drugs/2/drug-3766-2250/omeprazole-oral/omeprazole-delayed-release-tablet-oral/details

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Pantoprazole and omeprazole are both medicines from the class of medications called proton pump inhibitors (PPIs). The approved uses for pantoprazole and omeprazole differ slightly, but they are all disorders related to too much stomach acid. Continue reading

Famotidine is usually the first choice to treat occasional heartburn if your symptoms occur less than two times per week. It can be used as needed, provides quick relief (within 15 to 30 minutes), and is usually less expensive than omeprazole. Omeprazole may be an option if your heartburn occurs two or more days per week. Both products are available without a prescription. Continue reading

Yes, you could take omeprazole in the morning and famotidine at night but there are not many studies investigating this approach. Preliminary results suggest that taking your medication this way may provide superior control of gastric acid secretion at night without compromising the effectiveness of omeprazole in the morning. More research is needed. Continue reading

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