Methylprednisolone Acetate Injection Shortage

• • Amneal has methylprednisolone acetate injection available.[1]
  • Eugia has methylprednisolone acetate injection available.[2]
  • Pfizer has Depo-Medrol available. This product was not affected by the tornado in Rocky Mount.[3]
  • Sagent has methylprednisolone acetate injection available.[4]
  • Teva is not currently marketing methylprednisolone acetate.[5]

• • Depo-Medrol injection, Pfizer, 20 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0274-01
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3073-01
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3073-03
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 00009-0280-03
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 10 mL multiple dose vial, 25 count, NDC 00009-0280-52
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0280-02
  • Depo-Medrol injection, Pfizer, 40 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0280-51
  • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 00009-3475-01
  • Depo-Medrol injection, Pfizer, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 00009-3475-03
  • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 00009-0306-02
  • Depo-Medrol injection, Pfizer, 80 mg/mL, 5 mL multiple dose vial, 25 count, NDC 00009-0306-12
  • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1573-01
  • Methylprednisolone Acetate injection, Amneal, 40 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1573-05
  • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 1 count, NDC 70121-1574-01
  • Methylprednisolone Acetate injection, Amneal, 80 mg/mL, 1 mL single dose vial, 25 count, NDC 70121-1574-05
  • Methylprednisolone Acetate injection, Eugia US, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 55150-0313-01
  • Methylprednisolone Acetate injection, Eugia US, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 55150-0314-01
  • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 10 mL multiple dose vial, 1 count, NDC 25021-0820-10
  • Methylprednisolone Acetate injection, Sagent, 40 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0820-05
  • Methylprednisolone Acetate injection, Sagent, 80 mg/mL, 5 mL multiple dose vial, 1 count, NDC 25021-0821-05

Estimated Resupply Dates

• • All currently marketed presentations are available.

Alternative Agents & Management

• • The table below lists possible alternatives for patients who receive injectable corticosteroid suspensions.

  Table 1. Alternative agents for disorders commonly treated injectable corticosteroid suspensions.6-7

  Intra-articular injections for disorders such as rheumatoid arthritis and bursitis	Betamethasone acetate/betamethasone sodium phosphate
  Intralesional injections	Triamcinolone acetonide <40 mg per treatment Methylprednisolone acetate 20 to 40 mg per treatment for large lesions

  
  

References

• 1. Amneal (personal communication). August 20, and December 16 and 17, 2021, August 26, 2022; February 23, and July 7, 2023.
  2. Eugia (personal communication. June 28, and August 4, 2023.
  3. Pfizer (personal communication). August 20, September 17, November 19, December 10, 2021, and July 1, August 26, 2022; March 10, April 7, and August 4, 2023.
  4. Sagent (personal communication. July 22, August 26, 2022; March 9, April 6, and August 3, 2023.
  5. Teva (personal communication). August 20, September 17, November 12, December 10, 2021, July 1, August 26, 2022; March 10, and April 7, 2023.
  6. Lexicomp Online. Hudson, OH: Wolters Kluwer Clinical Drug Information, Inc; 2018.
  7. Dexamethasone sodium phosphate injection [package insert]. Lake Zurich, IL: Fresenius Kabi; 2021.