Sulfur Hexafluoride Dosage

Medically reviewed by Drugs.com. Last updated on Dec 28, 2023.

Usual Adult Dose for Diagnostic

For Intravenous Injection:
Echocardiography: 2 mL as an IV injection
Ultrasonography of the liver: 2.4 mL as an IV injection

Comments:

• Reconstitute prior to administration; consult manufacturer product information.
• May repeat dose one time during a single examination.
• Follow each injection with an IV flush of 5 mL of 0.9% sodium chloride.
• Avoid intra-arterial injection.

Use:

• To opacify the left ventricular chamber and improve the delineation of the left ventricular endocardial border in patients with suboptimal echocardiograms
• To localize and characterize hepatic focal lesions through ultrasonography

Usual Pediatric Dose for Diagnostic

For Intravenous Injection:
Echocardiography: 0.03 mL/kg as an IV injection up to a maximum of 2 mL per injection
Ultrasonography of the liver: 0.03 mL/ kg as an IV injection, up to a maximum of 2.4 mL per injection
Ultrasonography of the Urinary Tract: 1 mL after reconstitution (the bladder can be refilled with 0.9% sodium chloride injection for a second cycle of voiding and imaging, without the need of a second dose of this drug.

Comments:

• Reconstitute prior to administration; consult manufacturer product information.
• Follow each injection with an IV flush of 0.9% sodium chloride.
• Avoid intra-arterial injection.

Use:

• To opacify the left ventricular chamber and improve the delineation of the left ventricular endocardial border in patients with suboptimal echocardiograms
• To localize and characterize hepatic focal lesions through ultrasonography
• To evaluate vesicoureteral reflux with ultrasonography in pediatric patients.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active ingredient or any of its components, such as polyethylene glycol (PEG).

US BOXED WARNING:

• SERIOUS CARDIOPULMONARY REACTIONS: Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following the injection of ultrasound contrast agents, including sulfur hexafluoride lipid microspheres. Most serious reactions occur within 30 minutes of administration. Assess all patients for the presence of any condition that precludes administration. Always have resuscitation equipment and trained personnel readily available.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For single use only; discard unused portions appropriately.
• Do not administer by intra-arterial injection.
• Consult product information for reconstitution and administration instructions.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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