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Doxycycline User Reviews & Ratings (Page 3)

Brand names: Vibramycin, Monodox, Oracea, Doryx, Adoxa, Doxy 100, Acticlate, Mondoxyne NL, Targadox, Okebo, LymePak, Uracil, Doxy 200, Doryx MPC, Doxy-D, Oraxyl, Doxy-Caps, Alodox, Morgidox, Adoxa Pak, Avidoxy Adoxa TT Adoxa CK …show all brand names

Doxycycline has an average rating of 6.4 out of 10 from a total of 1,613 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Doxycycline

  • Chuck
  • Taken for less than 1 month
  • January 5, 2019

For Pneumonia "I let cough go untreated for 4 weeks because of no insurance, didn't want to create another bill I couldn't pay, and by end of week four I started coughing up blood so went to clinic. Pneumonia diagnosis. Was given doxycycline 100 mg x2 daily for 7 days. I'm on day two and already lungs are clear. Second day had a little stomach upset but I'd not drink much water that time. That is the key...drink water, drink water and drink water. Other than that one instance, no stomach trouble at all. It's a strong antibiotic and it works great, so glad I wasn't given amoxicillin which always tears my stomach up and works nowhere near as good as this has so far. Fist time using it and I'm thoroughly impressed so far. Tough out the stomach issues if you have any, again drink that water, cannot stress enough, not only for this drug but for helping the body to expel the mucous. Not cokes, not coffee or any caffeine, it's a diuretic and will keep you dehydrated."

10 / 10
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  • scass
  • December 23, 2019

For Acne "About 8 months ago, my skin suddenly went from clear to having huge, painful hormonal breakouts. My doctor recommended doxycycline so I started taking it. It took around 2 (very frustrating) months to start seeing a difference, but ever since then my skin has cleared up. I still occasionally get breakouts, but from things other than hormones (diet, not washing face, etc.). Reading through these reviews, this doesn’t work for everyone, but I recommend at least trying it, especially if you are dealing with hormonal, cystic acne. Things I’ve learned: -don’t take it before lying down -don’t take it on an empty stomach -take it with a large glass of water and eat afterwards -from extensive internet research, it seems like doxycycline normally takes 8-10 weeks before you start seeing a difference and 12 before the full effects -works best when combined with differin gel (available at a drug store without a prescription), moisturizer and a gentle cleanser"

9 / 10
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68 Report
  • smart...
  • Taken for less than 1 month
  • March 2, 2017

For Urinary Tract Infection "Started taking these at lunch time. By night time, the pain I previously experienced in my urinary tract had subsided a great deal. Had me cured by the end of my treatment. Didn't experience any headaches or stomach problems. Top notch."

10 / 10
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Frequently asked questions

  • Doctor
  • September 3, 2020

For Acne "I am doctor and took doxycycline 100mg for acne on face and back. It works and clears up skin in about two weeks. However, major complaint is that it causes skin darkening/hyperpigmentation. I have brown complexion and spend less than 5 minutes a day in sun but still turned several shades darker after just three weeks of taking it."

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  • Anony...
  • Taken for 1 to 6 months
  • September 16, 2019

For Lyme Disease "I started feeling really bad and went to the doctor and just happened to remember taking a tick off me so I asked them about it, after bloodwork tested positive for lyme and rocky mountain spotted fever. I have taken 2 rounds of doxycycline and still testing positive for it. I have now gotten to where all I want to do is sleep and my whole body hurts and is so weak that I literally cannot stand sometimes. I don't know what they will do next but already have diabetes and heart problems so I hope they figure something out soon. For anyone who thinks it is no big deal, this is completely different than just being tired, its almost like being paralyzed. Even with all my other medical issues I have always been able to push myself to go but I can't seem to do that with this. I'm afraid the longer I have it the more damage its going to do."

5 / 10
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Are you taking this medicine?

  • Aly...
  • Taken for less than 1 month
  • June 30, 2017

For Lyme Disease "I'm 24 yrs old. When I was only 4 I started experiencing crazy symptoms. Constant eye twitching, joint pain everywhere.. (Especially my hands) It wasn't until I turned 22 that a Dr thought to test me for Lyme Disease! After almost 20 yrs of searching for a diagnosis & treatment! I immediately was started on Doxy (100mg 2xDaily for a month) & referred to I.D. DR. I didn't even make it 3 days on the Doxy cuz the HERX! I wanted to die! Was then switched to a different antibiotic & again, only made it a few days on it because of how unbearable it was. A year later & I'm trying the Doxy again. Only 2 days in, feel like I'm dying. Whoever thinks Chronic Lyme isn't real, let me infect you & not get treated for years. Then let's see what you think!"

7 / 10
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  • Vonnie
  • Taken for 6 months to 1 year
  • September 30, 2020

For Upper Respiratory Tract Infection "Been poorly for 4 weeks I have COPD & usually have a rescue pack containing steroids & doxycycline with all this covid about docs wouldn’t give me rescue pack until I got covid test which came back negative. So it was nearly a week into being poorly I finally got doxycycline but no steroids. They cleared my upper tract infection but days later it came back so docs have now finally given me steroids & more doxycycline but a ten day course instead of seven days. I’m praying I finally get rid of this nasty infection as I feel so drained . Think the moral of my story if I had rescue pack in at the start of infection I wouldn’t have been as poorly as I have been I’ve always had rescue pack at hand for my COPD of steroids & doxcycline & felt better soon after taking them Amoxcillin didn’t help at all"

10 / 10
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More FAQ

  • momof...
  • August 4, 2014

Monodox (doxycycline) for Acne "My 15-year-old daughter started on this 2.5 weeks ago. Week 1, we saw no change. Week 2, the acne was significantly worse (the medicine paper warns that this may happen). As soon as Week 3 started, like magic, her face started to clear. We are happy with the results and hopeful for continued improvement."

9 / 10
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  • night...
  • September 23, 2019

For Bacterial Infection "I was prescribed doxy because of an allergy to penicillins. I did have the headache on this. My infection is better, have I had some crusting sores that had not been healing that are now better. Also a couple of sore teeth are no longer sore. I read up on how to take it as I wanted it to work - be sure not to eat for 2 hours before or an hour after for best absorption. Drink 8 oz of water with it - this does help to wash it down and with any stomach issues after. Don't lie down for at least 30 min after, preferably for up to an hour after, as it can cause esophageal irritation if you lie down. If you take any supplements containing calcium or magnesium, take those several hours after your last dose of doxy as they interfere with it. If you feel a little queasy after taking it, drink more water and wait a bit before trying food as a remedy."

8 / 10
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  • Allma...
  • Taken for less than 1 month
  • June 16, 2020

For Bacterial Infection "cat scratch fever is not just a Ted Nugent song, I got it and it sucks. This medicine definitely works, and fast in my case. HUGE NEGATIVE is I cannot stomach the doxycycline. I am constantly nauseous, I eat breakfast before my morning dose, lots of water, and still suffer extreme nausea. After day 2 I was struggling to eat breakfast I'm trying to stick it out 4 more days, but I'm struggling."

8 / 10
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  • Bumbo...
  • Taken for 1 to 6 months
  • January 20, 2017

For Lyme Disease "10+ years of Lyme, started having serious neurological symptoms (difficulty speaking, memory loss, tremor, vertigo and feeling of going crazy). Started a protocol of: - continuously: 2x200mg daily of doxycycline - a month of: "4 days on / 3 days off" of 1x500mg azithromycin, then - a month of: "5 days on / 2 days off" of 500mg tinidazole - after each month: 5 days of 100mg fluconazole - repeat - continuously: lots of probiotics, healthy diet and vitamin supplements I'm starting the 4th month, feeling *much* better (though symptoms return periodically, milder though). First 2 months were very harsh (feeling worse, sweating like crazy, sleepless and anxious). People advocating against long-term antibiotics haven't experienced real Lyme."

9 / 10
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  • Dinaxo
  • October 30, 2014

For Acne "I've been taking Doxycycline 50 mg once a day for my acne for about 3 weeks now and I'm finally seeing results. My skin is looking so good and better than ever. I'm so happy I can cry. The first 2 weeks seemed to almost make it worse but I didn't give up and I'm glad I didn't. I recommend it!"

8 / 10
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  • LisaK
  • October 13, 2014

For Upper Respiratory Tract Infection "I've been taking Doxycycline for a few days now for bronchitis/pneumonia. I take it twice a day. The dose in the morning makes me nauseous and I vomited once. Other than the extreme list of interactions with food and other medications, I would take it again for my illness. It's potent and so far seems to be clearing up my lungs and sinuses!"

10 / 10
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  • Sab
  • Taken for less than 1 month
  • May 16, 2020

Acticlate (doxycycline) for Acne "DO NOT TAKE THIS. I was prescribed Acticlate in 2015 and took it for about a month for my acne. It gave me permanent BLIND SPOTS. It’s been 5 years and they’re still present. I have read other people who this has happened to. Look up “doxycycline blindness”. Obviously medications are different for everyone, but I was perfectly healthy and not expecting to go blind."

1 / 10
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  • debbie
  • Taken for less than 1 month
  • November 10, 2019

For Bacterial Infection "I went to walk in clinic for sinus infection. I was given this medication doxycycline for the 1st time. I will never get accept a prescription for it again. On antibiotics I usually I feel better in a day or 2. On doxycline it took at least a week before symptoms started to clear up. I have been tired and had a severe head ache since I got the med. My body hurts and I still have the infection. I have taken the meds for 8 days. I am not taking the last 2 days, the pressure in my head is so bad I'm afraid it may give me a stroke. I have no idea why the walk in clinic gave me this medication if the side effects are so bad. But I took it, but never again."

3 / 10
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  • greg
  • August 18, 2020

For Upper Respiratory Tract Infection "I had been coughing for over a week non stop so much that I vomited, took 2 first day within hours my chest had cleared 90%, no side effects yet but even if i get some, it is nothing compared to the chest infection, its a wonder drug"

10 / 10
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  • Eliza...
  • July 6, 2016

For Urinary Tract Infection "I battled a nasty UTI for over a month & went through 3 different antibiotics till my doctor finally gave me this one. Makes you terribly sick to your stomach but in the end is completely worth it!! Felt completely back to normal in 2 days!!"

7 / 10
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  • Gigis...
  • July 12, 2013

For Lyme Disease "I found a bright red rash on my arm after planting some flowers and vegetables in my yard. I thought at first it was a yellow jacket sting but I never felt it. But after a few days my arm began to hurt, and the rash spread. Not a true bulls-eye though. My doctor saw me from across the crowded waiting room and pointed to me and said Lyme. I was prescribed Doxycycline 100mg 2x a day for 14 days. I was unable to take this medicine on an empty stomach, because I had severe nausea and diarrhea but didn't want to reduce the effectiveness so ate a little something. It made me sleepy and sometimes anxious and sometimes dizzy but not enough to stop medicines. I pray this Lyme disease is gone for good."

9 / 10
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  • Dying
  • Taken for less than 1 month
  • October 18, 2019

For Bacterial Infection "Initially was prescribed an antibiotic that interacted negatively with a drug I already take. Was then prescribed doxy. Tried to be optimistic as I was really sick with a chest infection I believe bronchitis the doctor didn't really seem to know. That should have been my first clue. Anyway so my first sign was my lips got really puffy. Then it felt like I was being choked. Keep in mind I already can't breathe from my illness! I make it thru the night but the next day the stomach pain starts. Bowels working as normal. I take 4 pills total before it gets to my mind. I feel so jittery that I can't stand myself. Anyway I am giving up I can't take anymore. I'm literally sitting here waiting for it to leave my system. It seems dramatic but I feel like I'm dying. Hate this medication!!"

2 / 10
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  • bigjo...
  • March 6, 2009

For Bacterial Infection "I've been sick for 3 years with a sinus infection, bacterial infection, middle ear infection, respiratory infection and so on - (was working in the Drains) - couldn't get rid of it. Have too to date (with Proof) 400 prescribed tablets from the doctors, (not including all the off the shelf one's I got myself (another 3/400). Anyway to cut a long story short, I have been on these doxycycline tablets for 2 weeks now (100MG a day) and am feeling a lot better. It's breaking down all the mucus etc. I can smell again now so if you have a massive sinus infection GET THIS - IT WORKS."

10 / 10
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140 Report
  • zombri
  • Taken for 1 to 2 years
  • February 24, 2020

For Acne "I used doxycycline off and on about 2 years. Each time it would help my skin but when I stopped taking it, my face would break out in horrible, cystic acne. I stopped taking it about a week ago once again. Broke out all around my nose, chin, forehead and cheek area with painful acne. Not going to use this drug anymore."

2 / 10
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  • alex
  • November 10, 2019

For Bacterial Infection "I told the P.A. that I was on my last pill for Zithromax . She told me that I need to stop taking it and start taking this poisonous ATB (doxycycline) .After the first pill ,I started experiencing diarrhea ,the second time ,it got worse that I had to go to the bathroom every 15 mins during the night .I was physically and mentally drained the next day ,but forced myself to work. To make matter worse, my respiratory infection exacerbated and developed hoarse voice. It has been 3 days ,since I took the 2nd pill and still going to the bathroom every 20 mins. Yesterday I took lomotil to control the urge for when I was at work. I ate lots of bananas ,white rice etc ,but to no avail. Now my anus is so irritated. Who ever ,prescribed this for bacterial infection should be told they have violated their oath of " DO NO HARM !""

1 / 10
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  • Sonja
  • Taken for less than 1 month
  • July 14, 2021

For Chlamydia Infection "Before taking doxcycline my symptoms were not really showing as much, but as soon as the third day hit, my symptoms got worse and now it’s more discharge and feeling very hot. I hope it works, I have to take it for 7 days twice and day and I’m on day 6."

7 / 10
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  • Starrr
  • Taken for 6 months to 1 year
  • July 17, 2014

For Bacterial Infection "This is the only medication that actually can clear the infections I get in my jaw and teeth, it works fast and really good, but the side effects can be unbearable at times. Extreme nausea, vomiting are the worst. The only way I've found to sometimes help with the vomiting is to take with a meal, which works most of the time, but not always."

10 / 10
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  • Janci...
  • June 19, 2018

For Lyme Disease "I am a 55 year old woman and was prescribed Doxycycline Hyclate 100mg for Lyme Disease. I took it twice a day for 30 days. During the last week of treatment, I noticed how I started to feel depressed: I found everything and everyone to be irritating, and I just wanted to be left alone. Yesterday was my first day without the medication, and I spent the most awful night of my life: I experienced vivid suicidal thoughts, was contemplating ways to end my life, and even wrote a letter to my children. The next day, I browsed the Internet and noticed I was not alone! I feel the company should absolutely list suicidal thoughts as a side effect of their drug, not only for adolescents, but for adults also. This way, family members and doctors could be warned and keep a close eye on every person to whom this drug is prescribed. If you've experienced suicidal thoughts while using this medication"

7 / 10
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65 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.