I have been taking spironolactone for 8 weeks for acne. I haven't experienced much for side effects except for extremely dry lips! The corners even crack open. I am constantly using lip balm and carmex. I'm wondering if anyone else has had this issue? Did it go away with time? It's so bad I am wondering if I'll have to discontinue the medication. I hope not though as I've tried EVERYTHING short of accutane