Skip to main content

Ambien, Lunesta, Sonata: What Are the 'Z Meds' for Sleep?

Medically reviewed by Carmen Pope, BPharm. Last updated on March 8, 2024.

By Ernie Mundell HealthDay Reporter

FRIDAY, March 8, 2024 -- Ambien, Lunesta, Sonata: Millions of bleary-eyed Americans turn to this class of so-called "Z-drugs" to get restful sleep.

But how do these drugs work, and do they come with risks?

Experts at the U.S. Food and Drug Administration have issued an advisory to boost awareness about the meds.

All of these medications -- generically known as zolpidem (Ambien, Ambien CR, Edluar and Zolpimist), eszopiclone (Lunesta) and zaleplon (Sonata) -- work by putting the brakes on brain activity, allowing you to drift off to sleep.

But the FDA warns that Z drugs also come with risks, most notably upping your odds for "complex sleep behaviors" -- things like sleepwalking, sleep driving, sleep cooking or even taking other medicines.

"The FDA has received reports of people taking these insomnia medicines and accidentally overdosing, falling, being burned, shooting themselves and wandering outside in extremely cold weather, among other incidents," the agency noted.

You might not even recall any of these behaviors occurring once you reawaken, according to the FDA.

The onset of complex sleep behaviors tied to Z drug use is also unpredictable. For some, the behavior can begin after the first dose, while for others it might begin much later into use.

Many sleep medicines can also cause daytime drowsiness, so avoid driving and other hazardous tasks under those circumstances.

Some other tips for safe use of Z drugs:

SOURCE: U.S. Food and Drug Administration, health advisory, March 6, 2024

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Read this next

Drive to Be 'Perfect' Parent Isn't Healthy, Survey Finds

THURSDAY, May 8, 2024 -- Parents striving to be “perfect” will never attain that goal, and the aim isn’t even healthy for their families, a new study says. The...

Popular Teens (Especially Girls) May Get Less Sleep

WEDNESDAY, May 1, 2024 -- Popular teens pay a price for being so well-liked by their peers, a new study shows. The popular crowd are less likely to get the 8 to 10 hours of sleep...

Melatonin Gummies to Get Safety Labeling, Child-Safe Bottles After Poisonings

TUESDAY, April 16, 2024 -- In the wake of a sharp rise in the number of young children accidentally eating melatonin supplements, an industry group has called for tougher safety...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.