Epcoritamab
Generic name: epcoritamab
Brand name: Epkinly
Dosage form: subcutaneous solution (bysp 4 mg/0.8 mL; bysp 48 mg/0.8 mL)
Drug class: Bispecific T-cell engagers (BiTE)
What is epcoritamab?
Epcoritamab is used to treat certain types of lymphoma (a cancer of the lymphatic system) in adults whose cancer has returned or did not respond to another treatment and who have received at least two previous cancer treatments.
Epcoritamab may also be used for purposes not listed in this medication guide.
Epcoritamab side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or diarrhea, fast or irregular heartbeats, feeling light-headed or very tired.
Epcoritamab may cause serious side effects. Call your doctor at once if you have:
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signs and symptoms of nervous system disorders--confusion, disorientation, muscle weakness, memory problems, tremors, trouble speaking or writing, tiredness, sleepiness, or seizures;
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low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
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signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding.
Your treatment with epcoritamab may be temporarily or permanently discontinued if you have certain side effects.
Common side effects of epcoritamab may include:
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tiredness;
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bone and muscle pain;
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stomach pain;
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fever;
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nausea, diarrhea; or
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bruising, swelling, warmth, redness, oozing, or bleeding where an injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Tell your medical caregivers if you have symptoms of a serious side effect, such as fever, chills, trouble breathing, vomiting, or severe tiredness.
Call your doctor if you have signs and symptoms of neurological problems such as trouble speaking, tiredness, tremors, confusion and disorientation, or weakness.
Before taking this medicine
Tell your doctor if you have an infection.
You may need to have a negative pregnancy test before starting this treatment.
May harm an unborn baby. Do not use if you are pregnant. Use effective birth control while using epcoritamab and for at least 4 moths after your last dose. Tell your doctor if you become pregnant.
Do not breastfeed while using epcoritamab, and for at least 4 months after your last dose.
How is epcoritamab given?
Follow all directions on your prescription label and read all medication guides or instruction sheets.
Epcoritamab is given by a healthcare provider as an injection under the skin, usually in the lower part of your stomach-area or thigh. Your doctor will decide how many treatment cycles you will receive of this medicine.
You may be given other medications to help reduce your risk of cytokine release syndrome (CRS). Keep taking these medicines for as long as your doctor has prescribed.
Your healthcare provider will check for CRS while you are being treated with epcoritamab and may treat you in a hospital if you develop signs and symptoms of CRS.
You will need medical tests.
Follow all storage instructions provided with epcoritamab. Your pharmacist can provide more information about how to store this medicine.
Related/similar drugs
Rituxan, Truxima, Monjuvi, Yescarta, Polivy, Xpovio, Breyanzi, Kymriah, Lunsumio, Columvi
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your epcoritamab injection.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid while receiving epcoritamab?
Avoid driving or hazardous activity until you know how epcoritamab will affect you. Your reactions could be impaired.
What other drugs will affect epcoritamab?
Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
Other drugs may affect epcoritamab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
More about epcoritamab
- Check interactions
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- Reviews (3)
- Side effects
- Dosage information
- During pregnancy
- Drug class: bispecific T-cell engagers (BiTE)
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Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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