How do I use Opill birth control?
- Take 1 tablet at the same time every day. It is important to take your pill at the same time of day (and no later than 3 hours from the time you took your tablet the day before).
- Use a condom (or another barrier method) every time you have sex during the first 2 days (48 hours) because it takes 2 days to start working.
- Opill is NOT for use as an emergency contraceptive and will not prevent pregnancy after unprotected sex.
Never skip your daily tablet, even if you do not have sex very often or have a change in your period (menstrual bleeding).
Each pack of Opill contains 28 pills. You can start your pack on any day. Do not take a break between packs. When you finish one pack (all 28 tablets), you should start the next pack the following day.
Opill works by thickening the cervical mucus, which helps block sperm from reaching the egg to prevent pregnancy. It may also prevent the ovaries from releasing eggs.
Learn more: What to do if you forget to take your Opill
If you are switching from another oral contraceptive, vaginal ring, or patch, start taking Opill the day after you stop the other method.
If you have taken an emergency contraceptive (for example, Plan B One Step) in the last 5 days, talk to your doctor or pharmacist before you start taking Opill.
Oral contraceptives do not protect against HIV, AIDS and other sexually transmitted diseases (STDs). Use condoms to prevent STDs.
If you have questions about how to take Opill, refer to the Drug Facts Label and consumer information leaflet found with your pack, or ask your doctor or pharmacist.
I forgot to take my Opill, what do I do?
If you are LESS than 3 hours late:
- take 1 tablet right away and go back to taking your tablet at your usual time the following day.
If you are MORE than 3 hours late OR you missed one or more tablets:
- you should take 1 tablet immediately, as soon as you remember. Then, go back to taking your tablet at your usual time. This means you may take 2 tablets in 1 day.
- Use a condom (or another barrier method) every time you have sex during the 2 days (48 hours) after you restart Opill, because it takes 2 days to start working again.
- Take a pregnancy test or talk to a doctor if your period is late after missing any tablets in the last month.
I took Opill, then I vomited. What should I do?
If you vomit or have severe diarrhea within 4 hours of taking your tablet:
- Use a condom (or another barrier method) every time you have sex for the next 2 days (48 hours) because the medicine may not have been fully absorbed.
- The next day, take your daily tablet at your usual time.
If you continue to vomit or have diarrhea, contact your healthcare provider right away.
What kind of side effects with Opill can I expect?
The most common side effects of Opill include:
- Changes in your menstrual period (bleeding)
- Headaches
- Dizziness
- Nausea
- Increased appetite
- Abdominal (stomach area) pain
- Cramps
- Bloating
If you start having migraine headaches or they get worse while using Opill, speak with your doctor right away. Keep taking your pill every day.
Seek medical help right away if you develop the following rare symptoms, which may be signs of liver problems: yellowing of the whites of your eyes or skin (especially with fever, tiredness, loss of appetite or dark colored urine).
Opill may cause changes to your period that are expected and normal, such as irregular spotting or prolonged bleeding. Some women will even stop having periods while taking Opill. Continue taking Opill exactly as directed.
Contact your healthcare provider AND continue taking this product every day if you develop repeated vaginal bleeding after sex, or you start having periods that last more than 8 days or have periods that are heavier than normal.
Do not use Opill if you are allergic to norgestrel (the active ingredient) or any of its other ingredients, such as the color additive FD&C yellow No.5 (tartrazine). You can find a list of ingredients on the package labeling or ask your pharmacist.
Do not use Opill if you have now, or have ever had, breast cancer.
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I missed my period while taking Opill, what do I do?
If you have missed two periods, or have missed one period and have also missed any doses of Opill, or suspect you are pregnant, you should take a pregnancy test or contact your doctor. Discontinue use of Opill if your test shows you are pregnant.
Signs that you may be pregnant might include:
- Missed periods
- Tender breasts
- Feeling nauseous (sick to your stomach)
- Fatigue
- Needing to urinate urgently or more frequently.
Are there any Opill drug intreactions?
Some medications can interact with the Opill, lowering its effectiveness. Talk to your doctor or pharmacist before you start Opill if you take, or are starting, any of these medicines:
- Seizures medicines (like barbiturates, carbamazepine, oxcarbazepine, phenytoin, topiramate, primidone)
- Tuberculosis drugs like rifampin or rifabutin
- A pulmonary hypertension medicine called bosentan
- An HIV/AIDS medicine called efavirenz
- Herbal products that contain hypericum perforatum (for example, St John's Wort)
Your doctor or pharmacist may advise you to use another form of contraception.
Do not use Opill with another form of hormonal birth control, such as another oral contraceptive pill, a vaginal ring, or any contraceptive patch, implant, injection or IUD (intrauterine device).
Tell your pharmacist and doctor about all the medicines you take, including prescription, over-the-counter (OTC), vitamins and herbal supplements. They can check any of your medicines for a drug interaction with Opill.
Related: When will Opill be available in stores?
This is not all the information you need to know about Opill (norgestreol 0.075 mg) for safe and effective use. Review the full Drug Facts Label and Consumer Information Leaflet and discuss this information and any questions you have with your doctor or pharmacist.
References
- Progestin-Only Hormonal Birth Control: Pill and Injection. American College of Obstetricians and Gynecologists (ACOG). Accessed July 29, 2023 at https://www.acog.org/womens-health/faqs/progestin-only-hormonal-birth-control-pill-and-injection
- Opill Drug Facts Label / Consumer Information Leaflet. US Food and Drug Information (FDA). Accessed July 13, 2023 at https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm
- Opill (0.075mg Oral Norgestrel Tablet) Information. US Food and Drug Administration (FDA). July 13, 2023. Accessed July 13, 2023 at https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/opill-0075mg-oral-norgestrel-tablet-information
- FDA Joint Advisory Committee Votes in Favor of Perrigo's Opill Daily Oral Contraceptive for OTC Use. Press release. May 10, 2023. Accessed July 13, 2023 at https://investor.perrigo.com/2023-05-10-FDA-Joint-Advisory-Committee-Votes-in-Favor-of-Perrigos-Opill-R-Daily-Oral-Contraceptive-for-OTC-Use
- Perrigo Announces U.S. FDA Approval for Opill® OTC Daily Oral Contraceptive. Press release. July 13, 2023. Accessed July 13, 2023 at https://investor.perrigo.com/2023-07-13-Perrigo-Announces-U-S-FDA-Approval-for-Opill-R-OTC-Daily-Oral-Contraceptive
- F.D.A. Approves First U.S. Over-the-Counter Birth Control Pill. New York Times. July 13, 2023. Accessed July 13, 2023 at https://www.nytimes.com/2023/07/13/health/otc-birth-control-pill.html
- FDA Approves First Nonprescription Daily Oral Contraceptive. US Food and Drug Administration (FDA). Accessed July 13, 2023 at https://www.fda.gov/news-events/press-announcements/fda-approves-first-nonprescription-daily-oral-contraceptive
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