Carboxymethylcellulose Calcium
Medically reviewed by Drugs.com. Last updated on Oct 4, 2023.
Excipient (pharmacologically inactive substance)
What is it?
Carboxymethylcellulose calcium is the calcium salt of carboxymethylcellulose and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing. Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness. [1]
Polymers of carboxymethylcellulose are also the active ingredient in many over-the-counter dry-eye or "natural tears" products, such as Refresh Tears or TheraTears Lubricant Eye Drops.
According to the FDA Select Committee on GRAS food substances, carboxymethylcellulose salts are virtually unabsorbed. Carboxymethylcellulose sodium is generally regarded as safe when used in normal quantities, and the same could be expected with the calcium salt. [2]
List of medications using Carboxymethylcellulose Calcium
- Cefdinir 300 mg
- Cefdinir 300 mg
- Cefdinir 300 mg
- Cefpodoxime Proxetil 100 mg
- Cefpodoxime Proxetil 200 mg
- Cilostazol 50 mg
- Irbesartan 300 mg
- Irbesartan 150 mg
- Irbesartan 150 mg
- Irbesartan 75 mg
- Irbesartan 300 mg
- Olanzapine (Orally Disintegrating) 5 mg
- Pioglitazone Hydrochloride 30 mg (base)
- Pioglitazone Hydrochloride 15 mg
- Pioglitazone Hydrochloride 45 mg (base)
- Pioglitazone Hydrochloride 30 mg (base)
- Pioglitazone Hydrochloride 30 mg
- Pioglitazone Hydrochloride 30 mg (base)
- Pioglitazone Hydrochloride 15 mg (base)
- Pioglitazone Hydrochloride 15 mg (base)
References
- [1]Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
- FDA’s SCOGS database; corn starch, Report No. 977050-51-3, 1979.; ID Code: 72; http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListing&id=72 Accessed October 17, 2011
Further information
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