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Drug Interactions between dronabinol and zaleplon

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

droNABinol zaleplon

Applies to: dronabinol and zaleplon

Using droNABinol together with zaleplon may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

droNABinol food

Applies to: dronabinol

Do not use alcohol while you are receiving treatment with droNABinol. This may increase nervous system side effects such as somnolence, dizziness, confusion, difficulty concentrating, and impairment in thinking and judgment. You should also avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of droNABinol. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Take droNABinol exactly as your doctor tells you to. Do not exceed the dose of droNABinol prescribed for you or use the medication more frequently or for a longer duration than prescribed by your doctor. Also, avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

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Moderate

zaleplon food

Applies to: zaleplon

Taking zaleplon with a high-fat or heavy meal may delay the onset of sleep. For faster sleep onset, zaleplon should not be administered with or immediately after a high-fat or heavy meal. This will make it easier for your body to absorb the medication. You should avoid the use of alcohol while being treated with zaleplon. Alcohol can increase the nervous system side effects of zaleplon such as dizziness and drowsiness. Some people may also experience impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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