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Drug Interactions between Cytoxan and Cardoxin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

cycloPHOSphamide digoxin

Applies to: Cytoxan (cyclophosphamide) and Cardoxin (digoxin)

Some cancer drugs like cycloPHOSphamide can cause damage to the intestinal lining and interfere with the absorption of digoxin. Blood levels and effects of digoxin may be reduced during chemotherapy. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition worsens or you experience increased symptoms of heart failure such as tiredness, swelling, fluid retention, sudden weight gain, difficulty breathing, shortness of breath, irregular heartbeat, or chest pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

digoxin food

Applies to: Cardoxin (digoxin)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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