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Voclosporin Dosage

Medically reviewed by Drugs.com. Last updated on Jan 26, 2024.

Applies to the following strengths: 7.9 mg

Usual Adult Dose for Lupus Nephritis

23.7 mg orally twice a day

Comments:


Use: In combination with a background immunosuppressive therapy regimen for the treatment of adult patients with active lupus nephritis

Renal Dose Adjustments

Mild or moderate renal dysfunction: No adjustment recommended.
Severe Renal Dysfunction (Estimated glomerular filtration rate 45 mL/min/1.73 m2 or less): Not recommended

Liver Dose Adjustments

Mild or moderate liver dysfunction (Child-Pugh A or B): 15.8 mg twice a day
Severe liver dysfunction (Child-Pugh C): Not recommended

Dose Adjustments

DOSAGE ADJUSTMENTS BASED ON ESTIMATED GLOMERULAR FILTRATION RATE (eGFR):


DOSAGE ADJUSTMENTS DUE TO DRUG INTERACTIONS:

Precautions

US BOXED WARNING:
MALIGNANCIES AND SERIOUS INFECTIONS:


CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Hemodialysis: Unknown

Other Comments

Administration Advice:


Storage Requirements:

Monitoring:

Patient Advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.