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Valoctocogene Roxaparvovec Dosage

Medically reviewed by Drugs.com. Last updated on Apr 8, 2024.

Applies to the following strengths: rvox 20 trillion vg/mL

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hemophilia A

6 × 10(13) vg/kg as a single IV infusion at a rate of 1 mL/min

Duration of therapy: Once

Comments:


Use: For the treatment of adults with severe hemophilia A without pre-existing antibodies to adeno-associated virus serotype 5

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Preparation technique:

IV compatibility:

General:

Monitoring:
Hepatic: Liver enzymes, ALT
Hematologic: Factor VIII activity, factor VIII inhibitors
Oncologic: Malignancy, hepatocellular carcinoma

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.