Triclabendazole Dosage

Usual Adult Dose for Fascioliasis

10 mg/kg orally every 12 hours for 2 doses

Comments:

If the dosage cannot be adjusted exactly, the dose should be rounded upwards.

Use: For the treatment of fascioliasis

Usual Pediatric Dose for Fascioliasis

6 years or older: 10 mg/kg orally every 12 hours for 2 doses

Comments:

If the dosage cannot be adjusted exactly, the dose should be rounded upwards.

Use: For the treatment of fascioliasis

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Known hypersensitivity to the active component, other benzimidazole derivatives, or any of the ingredients

Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Administer with food.
The tablets can be swallowed whole, divided in half and taken with water, or crushed and administered with applesauce; the crushed tablet with applesauce mixture is stable for up to 4 hours.

Storage requirements:

Store below 30C (86F) in original pack.

General:

The 250 mg tablets are functionally scored and divisible into 2 equal halves of 125 mg.

Monitoring:

Cardiovascular: ECG in patients with history of QTc interval prolongation, with history of symptoms consistent with long QT interval, or receiving drugs that prolong QT interval