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Thalidomide Dosage

Medically reviewed by Drugs.com. Last updated on Sep 30, 2024.

Applies to the following strengths: 50 mg; 100 mg; 150 mg; 200 mg

Usual Adult Dose for Leprosy - Erythema Nodosum Leprosum




Comments: May concomitantly start corticosteroids in patients with moderate to severe neuritis associated with a severe ENL reaction; can taper and discontinue steroid use when the neuritis has ameliorated.

Uses:

Usual Adult Dose for Multiple Myeloma

200 mg orally once a day with water, preferably at bedtime and at least 1 hour after the evening meal.


Comments: Consult the manufacturer product information for dexamethasone dosing recommendations.

Use: Treatment of newly diagnosed multiple myeloma (MM) in combination with dexamethasone.

Usual Pediatric Dose for Leprosy - Erythema Nodosum Leprosum

Age 12 Years and Older:




Comments: May concomitantly start corticosteroids in patients with moderate to severe neuritis associated with a severe ENL reaction; can taper and discontinue steroid use when the neuritis has ameliorated.

Uses:

Usual Pediatric Dose for Multiple Myeloma

Age 12 Years and Older:
200 mg orally once a day with water, preferably at bedtime and at least 1 hour after the evening meal.


Comments: Consult the manufacturer product information for dexamethasone dosing recommendations.

Use: Treatment of newly diagnosed multiple myeloma (MM) in combination with dexamethasone.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

Data not available.

Dose Adjustments

Multiple Myeloma (MM):


Erythema Nodosum Leprosum (ENL):

Precautions

US REMS: The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for this drug. It includes elements to assure safe use and an implementation system. For additional information: www.fda.gov/REMS or www.celgeneriskmanagement.com.

US BOXED WARNING:


Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

No adjustment recommended.

Other Comments

Administration Advice:


Storage Requirements:

General:

Monitoring:

Patient Advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.