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Terlipressin Dosage

Medically reviewed by Drugs.com. Last updated on Apr 3, 2023.

Applies to the following strengths: 0.85 mg preservative free

Usual Adult Dose for Hepatorenal Syndrome

Initial dose:
Day 1 to 3:
0.85 mg IV bolus injection every 6 hours over a period of two minutes

Day 4:

0.85 mg IV bolus injection every 6 hours over a period of two minutes

1.7 mg IV bolus injection every 6 hours over a period of two minutes

Duration of therapy: Until 24h after patient achieves a second consecutive SCr value of less than or equal to 1.5 mg/dL at least 2 hours apart or for a maximum of 14 days

Comments:

Use: To improve kidney function in adults with hepatorenal syndrome

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

No adjustment recommended.

Precautions

US BOXED WARNING:
SERIOUS OR FATAL RESPIRATORY FAILURE

Recommendation

CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Reconstitution technique:

General:

Monitoring:
Respiratory: Respiratory status (Oxygen saturation, Hypoxia)
Renal: Serum Creatinine
Metabolism: Hyponatremia, hypokalemia, hypomagnesemia, electrolyte disturbances

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.