Skip to main content

Tembexa Tablets Dosage

Generic name: BRINCIDOFOVIR 100mg
Dosage form: tablet, film coated
Drug class: Purine nucleosides

Medically reviewed by Drugs.com. Last updated on Feb 24, 2023.

Testing Before Initiating and During Treatment with TEMBEXA

Perform hepatic laboratory testing in all patients before starting TEMBEXA and while receiving TEMBEXA, as clinically appropriate.

Perform pregnancy testing before initiation of TEMBEXA in individuals of childbearing potential to inform risk.

Important Administration Instructions

Avoid direct contact with broken or crushed tablets or oral suspension. If contact with skin or mucous membranes occurs, wash thoroughly with soap and water, and rinse eyes thoroughly with water.

TEMBEXA Tablets

TEMBEXA tablets can be taken on an empty stomach or with a low-fat meal (approximately 400 calories, with approximately 25% of calories from fat). Swallow TEMBEXA tablets whole. Do not crush or divide TEMBEXA tablets.

TEMBEXA Oral Suspension

Take TEMBEXA oral suspension on an empty stomach. Shake oral suspension before use. Use an appropriate oral dosing syringe to correctly measure the total prescribed dose. Discard unused portion after completion of 2 prescribed doses.

For patients who cannot swallow, TEMBEXA oral suspension can be administered by enteral tube (naso-gastric or gastrostomy tubes) as follows:

Draw up prescribed dose with a calibrated catheter-tip syringe, and utilize this syringe to administer the dose via the enteral tube.
Refill the catheter-tip syringe with 3 mL of water, shake, and administer the contents via the enteral tube.
Flush with water before and after enteral administration.

Recommended Dosage

The recommended dosage of TEMBEXA in pediatric and adult patients is displayed in Table 1.

Table 1: Recommended Dosage in Pediatric and Adult Patients

Patient’s Weight (kg)

TEMBEXA Oral Suspension

(10 mg/mL)

TEMBEXA Tablet

(100 mg)

Less than 10 kg

6 mg/kg once weekly for 2 doses (on Days 1 and 8)

N/A

10 kg to less than 48 kg

4 mg/kg once weekly for 2 doses (on Days 1 and 8)

N/A

48 kg and above

200 mg (20 mL) once weekly for 2 doses (on Days 1 and 8)

200 mg (two 100 mg tablets) once weekly for 2 doses (on Days 1 and 8)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.