Skip to main content

Talazoparib Dosage

Medically reviewed by Drugs.com. Last updated on Oct 17, 2023.

Applies to the following strengths: 0.1 mg; 0.25 mg; 0.35 mg; 0.5 mg; 0.75 mg; 1 mg

Usual Adult Dose for Breast Cancer

1 mg orally once a day until disease progression or unacceptable toxicity

Comments:


Use: For the treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) HER2-negative locally advanced or metastatic breast cancer

Renal Dose Adjustments

Mild renal impairment: No adjustment recommended
Moderate renal impairment (CrCl 30 to 59 mL/min): 0.75 mg orally once a day
Severe renal impairment (CrCl 15 to 29 mL/min): 0.5 mg orally once a day

Liver Dose Adjustments

No adjustment recommended

Dose Adjustments

DOSE REDUCTIONS FOR ADVERSE REACTIONS:


DOSE MODIFICATIONS:

DOSE MODIFICATIONS FOR USE WITH P-GLYCOPROTEIN (P-GP) INHIBITORS:

Precautions

CONTRAINDICATIONS:


This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.