Prednisolone Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Aug 4, 2023.

Applies to the following strengths: sodium phosphate 0.125%; acetate 1%; sodium phosphate 1%; acetate 0.12%; acetate 0.125%; acetate 1% preservative-free

Usual Adult Dose for:

Iritis
Allergic Conjunctivitis
Keratitis
Cyclitis

Usual Adult Dose for Iritis

0.12% and 1% Ophthalmic Suspensions: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase dosing frequency if necessary

Comments:

If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
Care should be taken as to not discontinue therapy prematurely.
Anti-infective agents should me employed if a bacterial infection is present.
Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications when treating chronic conditions.

1% Ophthalmic Solution:

Initial dose: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) up to every hour during the day and every 2 hours during the night as needed
Maintenance dose: When a favorable response is observed, reduce dose to 1 drop every 4 hours; subsequent reduction to 1 drop 3 to 4 times a day may be adequate to control symptoms

Comments:

Duration of therapy varies depending upon the type of lesion and may extend from a few days to several weeks, based on therapeutic response.
Relapses, which are more common in chronic active lesions than in self-limited conditions, usually respond to retreatment.

Uses: For the treatment of steroid responsive mild to moderate noninfectious allergic and inflammatory disorders of the eye (e.g., allergic conjunctivits, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides); and for the treatment of corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies

Usual Adult Dose for Allergic Conjunctivitis

If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
Care should be taken as to not discontinue therapy prematurely.
Anti-infective agents should me employed if a bacterial infection is present.
Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications when treating chronic conditions.

1% Ophthalmic Solution:

Initial dose: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) up to every hour during the day and every 2 hours during the night as needed
Maintenance dose: When a favorable response is observed, reduce dose to 1 drop every 4 hours; subsequent reduction to 1 drop 3 to 4 times a day may be adequate to control symptoms

Comments:

Duration of therapy varies depending upon the type of lesion and may extend from a few days to several weeks, based on therapeutic response.
Relapses, which are more common in chronic active lesions than in self-limited conditions, usually respond to retreatment.

Usual Adult Dose for Keratitis

If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
Care should be taken as to not discontinue therapy prematurely.
Anti-infective agents should me employed if a bacterial infection is present.
Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications when treating chronic conditions.

1% Ophthalmic Solution:

Initial dose: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) up to every hour during the day and every 2 hours during the night as needed
Maintenance dose: When a favorable response is observed, reduce dose to 1 drop every 4 hours; subsequent reduction to 1 drop 3 to 4 times a day may be adequate to control symptoms

Comments:

Duration of therapy varies depending upon the type of lesion and may extend from a few days to several weeks, based on therapeutic response.
Relapses, which are more common in chronic active lesions than in self-limited conditions, usually respond to retreatment.

Usual Adult Dose for Cyclitis

If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
Care should be taken as to not discontinue therapy prematurely.
Anti-infective agents should me employed if a bacterial infection is present.
Withdrawal of treatment should be carried out by gradually decreasing the frequency of applications when treating chronic conditions.

1% Ophthalmic Solution:

Initial dose: Instill 1 to 2 drops into the conjunctival sac of the affected eye(s) up to every hour during the day and every 2 hours during the night as needed
Maintenance dose: When a favorable response is observed, reduce dose to 1 drop every 4 hours; subsequent reduction to 1 drop 3 to 4 times a day may be adequate to control symptoms

Comments:

Duration of therapy varies depending upon the type of lesion and may extend from a few days to several weeks, based on therapeutic response.
Relapses, which are more common in chronic active lesions than in self-limited conditions, usually respond to retreatment.

Renal Dose Adjustments

Data not available.

Liver Dose Adjustments

Data not available.

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available.

Other Comments

Administration advice:

For topical ophthalmic use only.
Suspension: Shake well before use.

Storage requirements:

Store in an upright position and keep tightly closed.
Protect from freezing.
Protect from light.

Patient advice:

Avoid allowing the tip of the dropper to touch any surface as this may cause contamination.
If irritation persists or develops, discontinue use and consult the prescribing physician.