Potassium Phosphate / Sodium Phosphate Dosage

Medically reviewed by Drugs.com. Last updated on Aug 4, 2023.

Applies to the following strengths: 250 mg-45 mg-250.5 mg; 250 mg-45 mg-298 mg; 305 mg-700 mg; 155 mg-350 mg; 250 mg-278 mg-164 mg; 250 mg-280 mg-160 mg

Usual Adult Dose for Hypophosphatemia

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)

Comments:

As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.

Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Adult Dose for Urinary Acidification

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)

Comments:

As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.

Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Hypophosphatemia

4 years and older: 1 tablet orally four times a day (with meals and bedtime)

Comments:

As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.

Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Urinary Acidification

4 years and older: 1 tablet orally four times a day (with meals and bedtime)

Comments:

As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.

Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

Renal Dose Adjustments

Contraindicated in severe renal impairment (renal function less than 30% of normal)

Liver Dose Adjustments

Use with caution

Dose Adjustments

Laxative effect:

Occasionally, some patients experience a mild laxative effect the first few days of phosphate therapy.
If lactation persists to an unpleasant degree, reduce the daily dose until it subsides, or discontinue the medication if necessary.

Precautions

CONTRAINDICATIONS:

Infected phosphate stones in the urinary tract
Severely impaired renal function (less than 30% of normal)
Hyperphosphatemia

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Contraindicated in severe renal impairment (renal function less than 30% of normal)

Other Comments

Administration advice:

Tablets should be taken with a full glass of water, with meals and at bedtime.

Storage requirements:

Store at room temperature; protect from light and moisture

Monitoring:

Periodically monitor renal function and serum calcium, phosphorous, potassium, and sodium.

Patient advice:

Advise patients to avoid antacids containing aluminum, magnesium, or calcium as they may prevent phosphate absorption.
Warn patients of the risk of passing old kidney stones when therapy is started.