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Mafenide Topical Dosage

Medically reviewed by Drugs.com. Last updated on Sep 9, 2024.

Applies to the following strengths: 85 mg/g; 5%

Usual Adult Dose for Bacterial Infection

Topical Cream: Apply with a sterile gloved hand to cleansed and debrided burn wounds once or twice a day, to a thickness of about 1/16 inch

Topical Solution: Grafted area should be covered with 1 layer of fine mesh gauze; an 8-ply burn dressing (cut to size of graft) should be wetted with this solution using an irrigation syringe and/or irrigation tubing until leaking noticeable; gauze dressing should be kept wet by:


Comments:

Uses:

Usual Adult Dose for Burns - External

Topical Cream: Apply with a sterile gloved hand to cleansed and debrided burn wounds once or twice a day, to a thickness of about 1/16 inch

Topical Solution: Grafted area should be covered with 1 layer of fine mesh gauze; an 8-ply burn dressing (cut to size of graft) should be wetted with this solution using an irrigation syringe and/or irrigation tubing until leaking noticeable; gauze dressing should be kept wet by:


Comments:

Uses:

Usual Pediatric Dose for Bacterial Infection

Topical Cream: Apply with a sterile gloved hand to cleansed and debrided burn wounds once or twice a day, to a thickness of about 1/16 inch

Topical Solution:
3 months or older: Grafted area should be covered with 1 layer of fine mesh gauze; an 8-ply burn dressing (cut to size of graft) should be wetted with this solution using an irrigation syringe and/or irrigation tubing until leaking noticeable; gauze dressing should be kept wet by:


Comments:

Uses:

Usual Pediatric Dose for Burns - External

Topical Cream: Apply with a sterile gloved hand to cleansed and debrided burn wounds once or twice a day, to a thickness of about 1/16 inch

Topical Solution:
3 months or older: Grafted area should be covered with 1 layer of fine mesh gauze; an 8-ply burn dressing (cut to size of graft) should be wetted with this solution using an irrigation syringe and/or irrigation tubing until leaking noticeable; gauze dressing should be kept wet by:


Comments:

Uses:

Renal Dose Adjustments

Acute renal failure: Caution recommended.

Liver Dose Adjustments

Data not available

Dose Adjustments

If acidosis occurs and becomes difficult to control, especially in those with pulmonary dysfunction, discontinuing therapy for 24 to 48 hours while continuing fluid therapy may help restore acid-base balance.

Precautions

CONTRAINDICATIONS:
Hypersensitivity to the active component

Topical Solution: Safety and efficacy have not been established in patients younger than 3 months.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Reconstitution/preparation techniques:

General:

Monitoring:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.