Iopromide Dosage
Applies to the following strengths: 150 mg/mL; 240 mg/mL; 300 mg/mL; 370 mg/mL
Usual Adult Dose for:
- Cerebral Arteriography
- Peripheral Arteriography
- Coronary Arteriography
- Left Ventriculography
- Computed Tomography
- Urography
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cerebral Arteriography
Cerebral arteriography, 300 mg Iodine/mL:
- Carotid arteries: 3 to 12 mL
- Vertebral arteries: 4 to 12 mL
- Aortic arch injection (4 vessel study): 20 to 50 mL
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Adult Dose for Peripheral Arteriography
Peripheral arteriography, 300 mg Iodine/mL:
- Subclavian or femoral artery: 5 to 40 mL
- Aortic bifurcation: 25 to 50 mL
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Adult Dose for Coronary Arteriography
Coronary arteriography and left ventriculography, 370 mg Iodine/mL:
- Right coronary artery: 3 to 14 mL
- Left coronary artery: 3 to 14 mL
- Left ventricle: 30 to 60 mL
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Adult Dose for Left Ventriculography
Coronary arteriography and left ventriculography, 370 mg Iodine/mL:
- Right coronary artery: 3 to 14 mL
- Left coronary artery: 3 to 14 mL
- Left ventricle: 30 to 60 mL
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Adult Dose for Computed Tomography
Contrast computed tomography, 300 mg Iodine/mL:
- Head: 50 to 200 mL
- Body, single phase contrast: 50 to 200 mL bolus injection, or 100 to 200 mL rapid infusion
- Body, multiple phase contrast: 50 to 200 mL total volume
- Phase 1: 100% contrast
- Phase 2: 20 to 60% contrast, using a power injector suitable for simultaneous contrast and saline injection
Contrast computed tomography, 370 mg Iodine/mL:
- Head: 41 to 162 mL
- Body, single phase contrast: 41 to 162 mL bolus injection, or 81 to 162 mL rapid infusion
- Body, multiple phase contrast: 41 to 162 mL total volume
- Phase 1: 100% contrast
- Phase 2: 20 to 60% contrast, using a power injector suitable for simultaneous contrast and saline injection
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Adult Dose for Urography
Excretory urography, 300 mg Iodine/mL: Approximately 300 mg Iodine per kg body weight (normal renal function patients)
Maximum total dose: 100 mL; 30 grams iodine
Comments:
- Volume and rate of injection vary depending on injection site and area being examined.
- Inject at rates approximately equal to the flow rate of the vessel being injected.
Usual Pediatric Dose for Computed Tomography
2 years and older:
Contrast computerized tomography, 300 mg Iodine/mL: 1 to 2 mL/kg
Maximum dose: 3 mL/kg
Usual Pediatric Dose for Urography
2 years and older:
Contrast computerized tomography, 300 mg Iodine/mL: 1 to 2 mL/kg
Maximum dose: 3 mL/kg
Usual Pediatric Dose for Coronary Arteriography
2 years and older:
Cardiac chambers and related arteries, 370 mg Iodine/mL: 1 to 2 mL/kg
Maximum dose: 4 mL/kg
Renal Dose Adjustments
Use with caution.
- Use the lowest necessary dose in renal dysfunction.
Liver Dose Adjustments
Data not available
Precautions
US BOXED WARNING(S):
- NOT FOR INTRATHECAL USE
- Inadvertent intrathecal administration may cause death, convulsions, cerebral hemorrhage, coma, paralysis, arachnoiditis, acute renal failure, cardiac arrest, seizures, rhabdomyolysis, hyperthermia, and brain edema
CONTRAINDICATIONS:
- Intrathecal use
- Preparatory dehydration (e.g. prolonged fasting and laxative use before administration) is contraindicated in pediatric patients due to the risk of renal failure.
Safety and efficacy have not been established in patients younger than 2 years.
Consult WARNINGS section for additional precautions.
Dialysis
This drug is dialyzable; however, no dose adjustment guidelines have been reported.
Other Comments
Administration advice:
- Administer at or close to body temperature.
IV compatibility:
- Do not mix with other medications
General:
- Hydrate patients as appropriate prior to and after administration.
More about iopromide
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- During pregnancy
- Drug class: non-ionic iodinated contrast media
- Breastfeeding
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