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Insulin Degludec Dosage

Medically reviewed by Drugs.com. Last updated on Mar 27, 2024.

Applies to the following strengths: 200 units/mL; 100 units/mL

Usual Adult Dose for Diabetes Type 1

Insulin-naive patients:
Initial dose: One-third to one-half the total daily insulin requirement subcutaneously once a day


Current insulin users:
Initiate at the same total daily dose of current long or intermediate-acting insulin subcutaneously once a day

Comments:

Use: To improve glycemic control in patients with type 1 diabetes mellitus.

Usual Adult Dose for Diabetes Type 2

Initial dose: 10 units subcutaneously once a day

Current insulin users:
Initiate at the same total daily dose of current long or intermediate-acting insulin subcutaneously once a day

Comments:


Use: To improve glycemic control in patients with type 2 diabetes mellitus.

Usual Pediatric Dose for Diabetes Type 1

Age: 1 year or older:

Insulin-naive patients:
Initial dose: One-third to one-half the total daily insulin requirement subcutaneously once a day


Current insulin users:
To minimize the risk of hypoglycemia: Initiate at 80% of the total daily long or intermediate-acting insulin dose subcutaneously once a day

Comments:

Use: To improve glycemic control in patients 1 year or older with type 1 diabetes mellitus.

Usual Pediatric Dose for Diabetes Type 2

Age: 1 year or older:
Initial dose: 10 units subcutaneously once a day

Current insulin users:
To minimize the risk of hypoglycemia: Initiate at 80% of the total daily long or intermediate-acting insulin dose subcutaneously once a day

Comments:


Use: To improve glycemic control in patients 1 year or older with type 2 diabetes mellitus.

Renal Dose Adjustments

Use caution; glucose-monitoring should be intensified and the insulin dose adjusted on an individual basis.

Liver Dose Adjustments

Use caution; glucose-monitoring should be intensified and the insulin dose adjusted on an individual basis.

Dose Adjustments

Elderly: Glucose-monitoring should be intensified in patients 65 years or older.

Dose adjustments may be necessary with changes in daily insulin requirements:


Dosage adjustments may be required when the brand, type, or species of insulin is changed; oral antidiabetic treatment may need to be adjusted as well.

Missed doses:

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 1 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Adults:
Pediatrics:


Preparation and Instructions for Use:

Storage requirements:

Compatibility:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.