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Insulin Aspart/Insulin Degludec Dosage

Usual Adult Dose for Diabetes Type 1

Doses should be individualized based on clinical response

Administer subcutaneously 1 to 2 times a day with any main meal


Insulin-naive patients:
Initial dose: One-third to one-half the total daily insulin requirement subcutaneously once or in divided doses twice a day with a main meal

Switching from Once or Twice Daily Premix Insulin:

Switching from Once or Twice Daily Basal Insulin:

Comments:

Use: To improve glycemic control in individuals with type 1 diabetes mellitus.

Usual Adult Dose for Diabetes Type 2

Initial dose: 10 units subcutaneously once a day with the main meal of the day
Maintenance dose: Adjust dose according to blood glucose measurements before breakfast (fasting); dose increases should occur no more frequently than every 3 to 4 days

Switching from Once or Twice Daily Premix Insulin:


Switching from Once or Twice Daily Basal Insulin:

Comments:

Use: To improve glycemic control in individuals with type 2 diabetes mellitus.

Usual Pediatric Dose for Diabetes Type 1

Doses should be individualized based on clinical response


1 year or older:

Administer subcutaneously once a day with any main meal

Insulin-naive patients:
Initial dose: One-third to one-half the total daily insulin requirement subcutaneously once a day with a main meal

Switching from Once or Twice Daily Premix Insulin:

Switching from Once or Twice Daily Basal Insulin:

Comments:

Use: To improve glycemic control in pediatric patients 1 year or older with type 1 diabetes mellitus.

Usual Pediatric Dose for Diabetes Type 2

1 year or older:


Initial dose: 10 units subcutaneously once a day with the main meal of the day
Maintenance dose: Adjust dose according to blood glucose measurements before breakfast (fasting); dose increases should occur no more frequently than every 3 to 4 days

Switching from Once or Twice Daily Premix Insulin:

Switching from Once or Twice Daily Basal Insulin:

Comments:

Use: To improve glycemic control in pediatric patients 1 year or older with type 2 diabetes mellitus.

Renal Dose Adjustments

Use caution; glucose-monitoring should be intensified and the insulin dose adjusted on an individual basis.

Liver Dose Adjustments

Use caution; glucose-monitoring should be intensified and the insulin dose adjusted on an individual basis.

Dose Adjustments

Elderly: Greater sensitivity is possible in older adults and hypoglycemia may be more difficult to recognize; glucose-monitoring may need to be intensified


Dosage adjustments may be required with changes to insulin regimens, changes in insulin, manufacturer, type, or method of administration; oral antidiabetic treatment may need to be adjusted as well.

Precautions

Safety and efficacy have not been established in patients younger than 1 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


DOSING INSTRUCTIONS:

Missed dose:

Preparation and Instructions for Use: See Manufacturer's Instructions for Use

Storage requirements:

Compatibility:

General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.