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Idelalisib Dosage

Medically reviewed by Drugs.com. Last updated on Nov 1, 2023.

Applies to the following strengths: 100 mg; 150 mg

Usual Adult Dose for non-Hodgkin's Lymphoma

150 mg orally 2 times a day until disease progression or unacceptable toxicity

Comments:


Uses:

Usual Adult Dose for Chronic Lymphocytic Leukemia

150 mg orally 2 times a day until disease progression or unacceptable toxicity

Comments:


Uses:

Usual Adult Dose for Lymphoma

150 mg orally 2 times a day until disease progression or unacceptable toxicity

Comments:


Uses:

Renal Dose Adjustments

No dose adjustment is necessary for patients with a CrCl greater than or equal to 15 mL/min.

Liver Dose Adjustments


Dose Adjustments

Pneumonitis:


Diarrhea:

Neutropenia:

Thrombocytopenia:

Infections:

Lymphocytosis:

Precautions

US REMS: The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for this drug. It includes a communication plan. For additional information: www.fda.gov/REMS.

US BOXED WARNINGS:
WARNING: FATAL AND SERIOUS TOXICITIES: HEPATIC, SEVERE DIARRHEA, COLITIS, PNEUMONITIS, INFECTIONS, and INTESTINAL PERFORATION:


CONTRAINDICATIONS:

Safety and efficacy have not been established in patients younger than 18 years.
This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.