Icatibant Dosage

Medically reviewed by Drugs.com. Last updated on May 25, 2023.

Applies to the following strengths: 10 mg/mL

Usual Adult Dose for:

Hereditary Angioedema

Additional dosage information:

Renal Dose Adjustments
Liver Dose Adjustments
Precautions
Dialysis
Other Comments

Usual Adult Dose for Hereditary Angioedema

30 mg subcutaneously once, in the abdominal area; may repeat every 6 hours if response is inadequate or symptoms recur.

Maximum dose: 90 mg/day

Renal Dose Adjustments

No adjustment recommended

Liver Dose Adjustments

No adjustment recommended

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

Initial treatment should be given under the guidance of a physician in a medical institution. Patients may self-administer this drug after initial training.
Attach the provided 25 gauge needle to the syringe hub and screw on securely. Do not use a different needle.
Disinfect the injection site and administer by subcutaneous injection over at least 30 seconds.

Storage requirements:

Store between 2 and 25C (36 to 77F). Do not freeze.
Store in carton until time of administration.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

Patient advice:

Advise patients to seek medical attention immediately if laryngeal symptoms occur.
In case of insufficient relief or recurrence after self-treatment, patients should seek medical attention.
Injection site reactions are reported in most patients after administration of this drug.
Advise patients not to drive or use machinery if they feel tired or dizzy.