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Futibatinib Dosage

Medically reviewed by Drugs.com. Last updated on Jul 12, 2023.

Applies to the following strengths: 4 mg (12 mg daily-dose); 4 mg (16 mg daily-dose); 4 mg (20 mg daily-dose)

Usual Adult Dose for Cholangiocarcinoma of biliary tract

Usual dose: 20 mg (five 4 mg tablets) taken orally once daily

Comments:


Use: Patients with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma harboring fibroblast growth factor receptor 2 (FGFR2) gene fusions or other rearrangements.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

DOSE MODIFICATION FOR ADVERSE REACTIONS:


DOSE MODIFICATION FOR RETINAL PIGMENT EPITHELIAL DETACHMENT (RPED):

DOSE MODIFICATION FOR HYPERPHOSPHATEMIA:
Serum phosphate 5.5 to 7 mg/dL:

Serum phosphate more than 7 to 10 mg/dL:

Serum phosphate more than 10 mg/dL:

DOSE MODIFICATION FOR OTHER ADVERSE REACTIONS:
Grade 3:

Grade 4:

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements:

Monitoring: Patients should be monitored for hyperphosphatemia throughout the treatment.

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.