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Fospropofol Dosage

Applies to the following strengths: 35 mg/mL

Usual Adult Dose for:

Usual Geriatric Dose for:

Additional dosage information:

Usual Adult Dose for Sedation

Standard Dosing Regimen for Sedation (in patients aged 18 to less than 65 years who are healthy or have mild systemic disease as categorized by the American Society of Anesthesiologists [ASA P1 or P2]):
RECOMMENDED DOSE: IV bolus of 6.5 mg/kg followed by supplemental doses of 1.6 mg/kg IV (25% of initial dosage) as needed to achieve the desired level of sedation (the dosage should be individualized and titrated to the level of sedation required for the procedure)

Comments:


Use: For monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures

Usual Geriatric Dose for Sedation

Modified Dosing Regimen for sedation (in patients 65 years of age or older or those with severe systemic disease as categorized by the American Society of Anesthesiologists [ASA P3 or P4]):
RECOMMENDED DOSE: 75% of the standard and supplemental dosing regimen

Comments:


Use: For monitored anesthesia care (MAC) sedation in adult patients undergoing diagnostic or therapeutic procedures

Renal Dose Adjustments

CrCl 30 mL/min or greater: No adjustment recommended

CrCl less than 30 mL/min: Limited safety and efficacy data are available. The manufacturer recommends caution.

Liver Dose Adjustments

The manufacturer recommends caution when initiating therapy in patients with hepatic impairment.

Dose Adjustments

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

US Controlled Substance: Schedule IV

Dialysis

Data not available

Other Comments

General:


Monitoring:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.