Skip to main content

Dyanavel XR Dosage

Generic name: AMPHETAMINE 2.5mg in 1mL
Dosage form: suspension, extended release
Drug class: CNS stimulants

Medically reviewed by Drugs.com. Last updated on Oct 26, 2023.

2.1 Pretreatment Screening

Prior to treating patients with DYANAVEL XR, assess:

  • for the presence of cardiac disease (i.e., perform a careful history, family history of sudden death or ventricular arrhythmia, and physical exam).
  • the family history and clinically evaluate patients for motor or verbal tics or Tourette’s syndrome before initiating DYANAVEL XR.

Recommended Dosage

The recommended starting dosage is 2.5 mg or 5 mg once daily in the morning. The dosage may be increased in increments of 2.5 mg to 10 mg per day every 4 to 7 days based on clinical response. The maximum recommended dosage is 20 mg once daily.

Administration Information

Administer DYANAVEL XR orally once daily in the morning with or without food.

DYANAVEL XR Extended-Release Oral Suspension

Instruct patients to read the “Instructions for Use” for complete administration instructions.

  • Ensure that the bottle adapter is firmly inserted into the bottle and do not remove once inserted.
  • Shake the bottle of DYANAVEL XR extended-release oral suspension well before every administration.
  • Use with the oral dosing dispenser provided by the pharmacist.

DYANAVEL XR Extended-Release Tablets

  • May be chewed or swallowed whole.
  • The 5 mg extended-release tablet is functionally scored and may be divided into equal halves (2.5 mg) at the score line.

Switching from Other Amphetamine Products

DYANAVEL XR extended-release oral suspension can be substituted with DYANAVEL XR extended-release tablets on a milligram-per-milligram basis.

If switching from other amphetamine products, discontinue that treatment, and titrate with DYANAVEL XR using the above titration schedule. Do not substitute for other amphetamine products on a milligram-per-milligram basis, because of different amphetamine salt compositions and differing pharmacokinetic profiles.

Dosage Modifications due to Drug Interactions

Agents that alter urinary pH can impact urinary excretion and alter blood levels of amphetamine. Acidifying agents (e.g., ascorbic acid) decrease blood levels, while alkalinizing agents (e.g., sodium bicarbonate) increase blood levels. Adjust DYANAVEL XR dosage accordingly.

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.