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Desflurane Dosage

Applies to the following strengths: 100%

Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Anesthesia

The administration of general anesthesia should be individualized based on patient response.

Inhalation: The minimum alveolar concentration (MAC), the concentration at which 50% of patients do not respond to surgical incision, ranges from 7.3% (25 years of age) to 6% (45 years of age). The concentration at which amnesia and loss of awareness occur (MAC - awake) is 2.4%. Surgical levels of anesthesia are achieved with concentrations between 2.5% and 8.5% with or without concomitant use of nitrous oxide.

Uses:

Usual Geriatric Dose for Anesthesia

The administration of general anesthesia should be individualized based on patient response.

MAC is reduced (5.2% at 70 years of age). The concentration at which amnesia and loss of awareness occur (MAC - awake) is 2.4%. Surgical levels of anesthesia are achieved with concentrations between 2.5% and 8.5% with or without concomitant use of nitrous oxide.

Uses:

Usual Pediatric Dose for Anesthesia

The administration of general anesthesia should be individualized based on patient response.

Surgical levels of anesthesia range from 5.2% to 10% with or without concomitant use of nitrous oxide.

Comments:


Use: For maintenance of anesthesia in infants and children after induction of anesthesia with agents and tracheal intubation

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Dose Adjustments

In patients with intracranial space occupying lesions this drug should be administered at 0.8 MAC or less, in conjunction with a barbiturate induction and hyperventilation (hypocapnia). Appropriate measures should be taken to maintain cerebral perfusion pressure.

Precautions

CONTRAINDICATIONS:


Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

OTHER COMMENTS:
Administration advice:


Storage requirements:

General:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.