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Delflex Dosage

Generic name: DEXTROSE MONOHYDRATE 1.5g in 100mL, SODIUM CHLORIDE 538mg in 100mL, SODIUM LACTATE 448mg in 100mL, CALCIUM CHLORIDE 18.4mg in 100mL, MAGNESIUM CHLORIDE 5.08mg in 100mL
Dosage form: intraperitoneal solution
Drug class: Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on Oct 2, 2024.

Basic Dosing Information

DELFLEX® is intended for intraperitoneal administration only. Not for intravenous or intra-arterial administration.

The mode of therapy, frequency of treatment, formulation, exchange volume, duration of dwell, and length of dialysis should be selected by the physician responsible for the treatment of the individual patient.

Utilize the peritoneal dialysis solution with lowest level of osmolarity consistent with the fluid removal requirements for that exchange.

Do not store solutions containing additives.

Administration Instructions

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit.

Do not heat in a microwave oven.

Get Ready

  1. Clean work surface and gather supplies:
    • Masks (enough for everyone in the room).
    • Warmed DELFLEX peritoneal dialysis bag with attached stay•safe exchange set.
    • stay•safe organizer, a stand-alone item provided separately.
    • Povidone iodine prefilled stay•safe cap, a stand-alone item provided separately.
    • IV Pole (optional).
    • Prescribed medication(s), if ordered by your healthcare provider.
  1. After removing the overwrap, check your DELFLEX solution bag(s) for (strength, clarity, amount, leaks, and expiration date). Do not use DELFLEX solution if leaks are found, the solution bag is damaged, and/or the solution is cloudy or discolored, or the product is expired. Color may vary from clear to slightly yellow but does not affect efficacy and may be used.

  1. Prepare supplies:
    1. Retrieve stay•safe catheter extension set and ensure clamp is closed.
    2. Tear the overwrap from the slit edge down the length of the inner bag to open.
    3. Wipe away any moisture from the solution bags. Some opacity may be observed in the plastic of the bag and/or tubing and is due to moisture absorption during the sterilization process. This is normal and does not affect the solution quality or safety. The opacity will diminish gradually.
    4. Visually check that the solution bag tubing is free from kinks. If kinks are present, straighten tubing to allow the solution to flow freely.
      Note: Retain DELFLEX peritoneal dialysis bag sample for manufacturer evaluation and notify your healthcare provider if any of the above defects are found.
    5. Put on mask. Wash your hands per facility protocol.
    6. Position the stay•safe organizer at the edge of your clean work surface or with the stay•safe holder on the IV pole.
  1. Remove color-coded cover:
    1. Turn the blue dial as directed by the arrow in the color-coded cover.
    2. Remove the color-coded cover from the stay•safe DISC. The blue dial will be in Position 1(●) DRAIN.
Figure
  1. Prepare organizer and solution bag:
    1. Place the stay•safe DISC and tubing into the organizer and tubing channels on the organizer.
    2. If you will be adding medication(s):
      1. Clean hands (as per facility's protocol).
      2. Clean the medication port as instructed by your healthcare provider.
      3. Add the medicine(s).
      4. Turn the bag upside down several times to mix the medicine(s).
    3. Hang the DELFLEX peritoneal dialysis solution bag on the IV pole and place the drain bag with the clear side up on the floor.
    4. Break cone of the administration port.
Figure
  1. Remove new stay•safe cap from its package and place stay•safe cap into the left notch of the organizer.
Figure
  1. Place stay•safe catheter extension set into organizer.
    1. Clean hands (as per facility's protocol).
    2. Place stay•safe catheter extension set into the right notch of the organizer.
    3. Ensure clamp of stay•safe catheter set is closed.
Figure
  1. Remove protective cap from stay•safe DISC and set aside.
Figure
  1. Connect stay•safe catheter extension set to the stay•safe DISC.
    1. Unscrew stay•safe catheter extension set from its cap.
    2. Immediately connect the stay•safe catheter extension to the stay•safe DISC.
    3. Open the white clamp of stay•safe catheter extension set and start DRAIN.
    4. Place discarded protective cap from stay•safe DISC onto the used stay•safe cap in the stay•safe organizer and discard.
Figure
  1. When DRAIN is complete:
    1. Turn blue dial to Position 2(●●), FLUSH for about 5 seconds.
    2. Make sure the line between solution bag and stay•safe DISC is fully primed.
Figure
  1. When FLUSH is complete:
    1. Turn blue dial to Position 3(⚪◐●), FILL to begin the fill of solution to your abdomen. Flow rate can be adjusted from slow (⚪) to moderate (◐) to fast (●).
Figure
  1. When FILL is complete:
    1. Turn blue dial as far as possible in Position 4(●●●●), PIN/CLOSE until you feel and/or hear a “click”.
    2. The stay•safe PIN located in the stay•safe DISC will automatically be released into the end of the stay•safe catheter extension set.
Figure
  1. When PIN/CLOSE is complete:
    1. Close the clamp of the stay•safe catheter extension set.
    2. Using aseptic technique, mask then wash hands as instructed by your healthcare provider.
    3. Unscrew protective cover from the new stay•safe cap and set aside.
Figure
  1. Disconnect from stay•safe DISC:
    1. Unscrew the stay•safe catheter extension set from the stay•safe DISC.
    2. Immediately attach the stay•safe catheter extension set with a PIN to the new stay•safe cap.
    3. Remove capped catheter extension set from organizer and secure to your abdomen.
Figure
  1. Complete treatment:
    1. Place protective cover from the new stay•safe cap on the stay•safe DISC connector to prevent drips.
    2. Weigh drain bag (as per facility's protocol).
    3. Record exchange results on treatment log.
    4. If an effluent sample is required:
      1. Use aseptic technique and facility protocols throughout collection.
      2. Scrub the drain bag's sample port hub with friction and an Isopropyl Alcohol 70% swab/prep pad for 15 seconds, and allow to dry for 30 seconds more.
      3. Withdraw the effluent sample directly from the sample port hub with a needle and a syringe.
    5. Discard the used tubing and solution (as per facility's protocol).
    6. Throw away the fluid and used exchange set as instructed by your healthcare provider. In case of cloudiness, save the fluid and the used exchange set and immediately contact your healthcare provider.

Compatible Medications

Compatible medications can be added via the medication port [ see Dosage and Administration ( 2.2) ]. The following medications have demonstrated stability with DELFLEX solutions: cefazolin, ceftazidime, gentamicin, and vancomycin [ see Clinical Pharmacology ( 12.3) ].

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.