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Deferiprone Dosage

Medically reviewed by Drugs.com. Last updated on Mar 20, 2024.

Applies to the following strengths: 500 mg; 1000 mg; 100 mg/mL

Usual Adult Dose for Thalassemia

Initial dose: 25 mg/kg, orally, 3 times a day (total daily dose: 75 mg/kg)
Maximum dose: 33 mg/kg, orally, 3 times a day (total daily dose: 99 mg/kg)

Comments:


Use: Treatment of transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Usual Adult Dose for Iron Overload

Initial dose: 25 mg/kg, orally, 3 times a day (total daily dose: 75 mg/kg)
Maximum dose: 33 mg/kg, orally, 3 times a day (total daily dose: 99 mg/kg)

Comments:


Use: Treatment of transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Usual Pediatric Dose for Thalassemia

8 years and older:
Initial dose: 25 mg/kg, orally, 3 times a day (total daily dose: 75 mg/kg)
Maximum dose: 33 mg/kg, orally, 3 times a day (total daily dose: 99 mg/kg)

Comments:


Use: Treatment of transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Usual Pediatric Dose for Iron Overload

8 years and older:
Initial dose: 25 mg/kg, orally, 3 times a day (total daily dose: 75 mg/kg)
Maximum dose: 33 mg/kg, orally, 3 times a day (total daily dose: 99 mg/kg)

Comments:


Use: Treatment of transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate.

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended for mild or moderate hepatic impairment.

Dose Adjustments

Precautions

US BOXED WARNING: NEUTROPENIA/AGRANULOCYTOSIS

Recommendations:

Safety and efficacy have not been established in patients younger than 8 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available.

Other Comments

Administration advice:


Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.