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Darunavir Dosage

Medically reviewed by Drugs.com. Last updated on Apr 30, 2024.

Applies to the following strengths: 600 mg; 300 mg; 800 mg; 400 mg; 75 mg; 150 mg; 100 mg/mL

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for HIV Infection

Therapy-Naive Patients and Therapy-Experienced Patients with No Darunavir Resistance-Associated Substitutions: Darunavir 800 mg plus ritonavir 100 mg orally once a day with food

Therapy-Experienced Patients with At Least 1 Darunavir Resistance-Associated Substitution or with No Baseline Resistance Information: Darunavir 600 mg plus ritonavir 100 mg orally twice a day with food

Pregnant Patients: Darunavir 600 mg plus ritonavir 100 mg orally twice a day with food

Comments:


Use: In combination with ritonavir and other antiretroviral agents, for the treatment of HIV-1 infection

Usual Pediatric Dose for HIV Infection

3 to less than 18 years:
Therapy-Naive Patients and Therapy-Experienced Patients with No Darunavir Resistance-Associated Substitutions:
Oral suspension:

or

Tablets and oral suspension:

Therapy-Experienced Patients with At Least 1 Darunavir Resistance-Associated Substitution:
Oral suspension:
or

Tablets and oral suspension:

Comments:

Use: In combination with ritonavir and other antiretroviral agents, for the treatment of HIV-1 infection

Renal Dose Adjustments

Moderate renal dysfunction: No adjustment recommended.
Severe renal dysfunction or ESRD: Data not available

Liver Dose Adjustments

Mild to moderate liver dysfunction: No adjustment recommended.
Severe liver dysfunction: Not recommended.

Comments:

Precautions

CONTRAINDICATIONS:
With Ritonavir:


Safety and efficacy have not been established in patients weighing less than 10 kg; this drug (plus ritonavir) is not recommended for use in patients younger than 3 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Comments:

Other Comments

Administration advice:


Storage requirements:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.