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Bupivacaine Liposome Dosage

Medically reviewed by Drugs.com. Last updated on May 6, 2024.

Applies to the following strengths: 1.3% (13.3 mg/mL)

Usual Adult Dose for Pain

Local Analgesia via Infiltration:


Regional Analgesia via Interscalene Branchial Plexus Nerve Block:
Maximum dose for interscalene brachial plexus nerve block: 133 mg (10 mg)

Comments:

Uses: For single-dose infiltration to produce postsurgical local analgesia and as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia.

Renal Dose Adjustments

Caution is recommended; risk of toxic reactions may be greater in patients with impaired renal function

Liver Dose Adjustments

Mild hepatic impairment: Use with caution
Moderate to severe hepatic impairment: Consider increased monitoring for local anesthetic systemic toxicity

Dose Adjustments

Dosing Examples for Local Analgesia via Infiltration:

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Reconstitution/preparation techniques:

Storage requirements:

IV compatibility:

General:

Monitoring: Perform careful and constant monitoring of cardiovascular and respiratory (adequacy of ventilation) vital signs and the patient's state of consciousness after injection of this drug.

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.