Acetaminophen / hydrocodone Alternatives Compared
Acetaminophen / hydrocodone | Cimzia | Methotrexate |
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Acetaminophen / hydrocodone | Cimzia (certolizumab) | Methotrexate |
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Prescription only
Acetaminophen/hydrocodone may be used to treat moderate-to-severe pain that is unrelieved by nonopioid analgesics. However, its use is limited by the dependence and addiction potential of the... View more |
Prescription only
Prescribed for Ankylosing Spondylitis, Crohn's Disease, Crohn's Disease - Maintenance, Crohn's Disease - Active, Non-Radiographic Axial Spondyloarthritis, Plaque Psoriasis, Psoriasis, Psoriatic... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Rheumatoid Arthritis
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More about Acetaminophen / hydrocodone | More about Cimzia (certolizumab) | More about Methotrexate | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Acetaminophen / hydrocodone has an average rating of 6.0 out of 10 from a total of 1333 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 34% reported a negative effect. |
Cimzia has an average rating of 6.7 out of 10 from a total of 88 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 22% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 332 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: acetaminophen / hydrocodone side effects in more detail. |
See also: Cimzia side effects in more detail. |
See also: methotrexate side effects in more detail. |
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Generic Availability | ||||||||||||||||||
Lower cost generic |
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all acetaminophen / hydrocodone prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all methotrexate prices |
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Dosage Form(s) Available | ||||||||||||||||||
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Brand Names | ||||||||||||||||||
Xodol, Zyfrel |
N/A |
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
3.8 hours |
336 hours |
15 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 635 drugs are known to interact with acetaminophen / hydrocodone:
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A total of 482 drugs are known to interact with Cimzia:
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A total of 695 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
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First Approval Date | ||||||||||||||||||
May 03, 1982 |
April 22, 2008 |
December 07, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.