Skip to main content

Ezetimibe User Reviews & Ratings (Page 4)

Brand names: Zetia

Ezetimibe has an average rating of 3.8 out of 10 from a total of 164 reviews on Drugs.com. 24% of reviewers reported a positive experience, while 62% reported a negative experience.

Reviews for Ezetimibe

  • Sam
  • Taken for 1 to 6 months
  • September 8, 2022

For High Cholesterol "My doctor prescribed this after statins caused horrible pain in the muscles. Then he prescribed, cholestermine, a powder resin, that caused little side effects, but my triglycerides shot up. I did learn that resin has to washed out of the mouth by brushing your teeth or it can rot teeth. I then tried red yeast rice and that caused the same pain as the statins. My doctor told me it contains lovastatin. He then put me on this Zetia or ezetimibe. I thought everything was okay at first, but I started coughing with water in the back of my throat and it felt like water was on my lungs. Then my back hurt continuously and my foot pain came back. Then I started having continuous diarrhea 3-4 times a day and even didn’t make it to the toilet a couple times. This is a horrible drug. I had my blood work done and my liver enzymes shot up on top of it."

1 / 10
Was this helpful?YesNo
15 Report
  • Riodosa
  • Taken for 5 to 10 years
  • August 4, 2018

For High Cholesterol "I have been on this number of years - maybe 7. I think the Ezetimibe was effective on reducing the cholesterol as designed however, I have had bouts of diarrhea for years like my stomach explodes and out it comes. The doctors have not come up with a cause and/or a solution. Lately I have reason to believe it is caused by the Ezetimibe that I take. It seems to come on me about 2 or 3 hours after I take it. Anybody else have this problem?"

6 / 10
Was this helpful?YesNo
37 Report
  • bob
  • Taken for 6 months to 1 year
  • December 17, 2020

Zetia (ezetimibe) for High Cholesterol "I started taking Ezetimibe in Feb. 2019. I can not tolerate statins. After 10 months I started to develop joint pain, muscle weakness, runny nose and was very tired. I checked my blood pressure. It was 213 over 120. I decided that ezetimibe could be the problem. I stopped taking Ezetimibe. After 2-1/2 days by blood pressure dropped to 152 over 94. I feel 100% better. There is a question that my liver could have bee damaged."

1 / 10
Was this helpful?YesNo
25 Report

Frequently asked questions

  • Mare
  • August 1, 2020

For High Cholesterol "Been taking ezetimibe 10mg about 3 weeks. I do get occasional diarrhea but my biggest problem is the bloating my stomach looks like I'm pregnant and I hate that feeling. I don't have any other symptoms."

5 / 10
Was this helpful?YesNo
27 Report
  • Janie
  • Taken for less than 1 month
  • March 27, 2023

Zetia (ezetimibe) for High Cholesterol "I was hoping this would work as I am statin intolerant. I began belching nonstop and had chest pain. I have never felt like this before. Quitting my one cup of coffee a day and anything else known to aggravate GERD had no impact. I also had leg pain starting from the buttocks all the way down through the arches of my feet. I rarely get ocular migraines but started to get them frequently. I’m off of it and feeling much better. A glass of wine or coffee does not bother me. It was the medication."

1 / 10
Was this helpful?YesNo
11 Report

Are you taking this medicine?

  • Flygirl
  • Taken for less than 1 month
  • February 23, 2018

For High Cholesterol "I was taking the name brand Zetia for many years after trying 5 different statins that caused leg cramps that had me jumping out of bed at night and no way to stop the horrendous pain. No, pickle juice and hot showers didn't work. Things were going well with the Zetia until my insurance company refused to cover the drug this year and said I had to take the generic ezetimibe. What a disaster! It was like doing a colonoscopy prep every day. I couldn't leave the house because I was constantly running to the bathroom with severe diarrhea that lasted about 8-10 hours until the drug wore off. It made it impossible to even go to work. I couldn't eat anything without it running right through me (that's how it controlled the cholesterol--nothing stayed with you). Frankly, I'd rather take NOTHING than go through that again."

Was this helpful?YesNo
38 Report
  • Marga...
  • Taken for 6 months to 1 year
  • August 5, 2021

Zetia (ezetimibe) for High Cholesterol "I was diagnosed with PAD and given statins which caused severe brain fog and confusion to the degree that my spouse though I had dementia. I changed to ezetimibe to reduce high cholesterol, but even though it is not listed for Zetia I still get the brain fog, although not quite as bad, I am afraid to stop taking them, has anyone suffered the same effects? I am also taking clopidrogal and high blood pressure medication. I am 79 years old."

3 / 10
Was this helpful?YesNo
21 Report

More FAQ

  • debs
  • Taken for less than 1 month
  • November 9, 2019

For High Cholesterol "My dr warned me that I may get stomach problems on ezetimibe , but I wasn't expecting the runs for hours on end and stomach pain. I've stopped it as I'm not sleeping and I'm constantly burping and it tastes awful, I messed up my bed and clothing."

1 / 10
Was this helpful?YesNo
30 Report
  • ejn
  • Taken for 1 to 6 months
  • March 18, 2017

For High Cholesterol "I have used this for a few months as I cannot take a statin due to muscle pains. During this period I developed a stiff shoulder that later progressed to a frozen shoulder. Worse, I had problems with focussed thinking, and because of my lack of focussed thinking I only noticed this at 6 weeks. As I am a teacher, I immediately quit using it. I was lucky this happened in the school holidays. I have no idea what it did for my cholesterol, as the second side effect I noticed was such that I felt unable to continue it."

2 / 10
Was this helpful?YesNo
42 Report
  • Sitinin
  • Taken for 2 to 5 years
  • February 22, 2018

For High Cholesterol "Was on Zetia 10mg daily for four years. Underwent numerous scans, testing, Ultrasounds & vascular studies to determine why I was having severe leg cramping every single day ( worse at night ) I discontinued Zetia by myself and legs had 100% return to normal. Unable to take statins due to joint pains but was assured this med was not the same."

2 / 10
Was this helpful?YesNo
38 Report
  • Milag...
  • Taken for 1 to 2 years
  • December 6, 2019

For High Cholesterol "My Doc believed my LDL and total cholesterol were too high. I was on Simvastatin 40mg. He added a script for 10mg Ezetimibe. 3 months later on Simvastatin 40 and Ezetimibe 10 my total Cholesterol improved 216 > 116. LDL improved 137 > 46. I was on Paleo diet (no fruit) before and after Ezetimibe. Now all cholesterol measures are well within normal range."

10 / 10
Was this helpful?YesNo
29 Report
  • JJano
  • Taken for less than 1 month
  • November 4, 2020

For High Cholesterol "I was on Zetia for a month but my hip burned so I stopped, much like other statins I had tried. I tried it again later and after a month both my hips burned. I stopped Zetia and the burning improved. It has been 6 months and my right hip still burns, and sometimes my left. I am done with statins. No drug is worth side effects like this. I will exercise more."

1 / 10
Was this helpful?YesNo
24 Report
  • Cindy
  • Taken for less than 1 month
  • May 20, 2019

For High Cholesterol "My cholesterol is/was at 235 and through a doppler discovered my left interior carotid artery is 100 percent occluded but got somewhat lucky with some strong collateral arteries. My doctor immediately put me on statins...a big no go on all of them, each one I tried (5) I had horrible side effects immediately. Fog like state, shortness of breath, muscle cramps, depression it was terrible. One of my sisters was put on Zetia with no side effects and her cholesterol went from over 300 down to 80. I begged my doctor to let me at least try it and I've just passed the 1 week mark with just a couple of small side effects, tingly legs twice and bloating. So far I love this ezetimibe however the proof will be in 2 months when my cholesterol is rechecked. I am a 65 yr old female."

8 / 10
Was this helpful?YesNo
30 Report
  • GCano
  • August 11, 2020

For High Cholesterol "I have been taking Ezetimibe, generic for Zetia, for one year with no side effects. With drug RX card I pay $25.00 every 90 days. My collesteral is down to 200 from 238, I still have to little good cholesterol but its better than the pain I get with Statins."

7 / 10
Was this helpful?YesNo
23 Report
  • Meena...
  • Taken for 1 to 6 months
  • November 1, 2021

For High Cholesterol "I have been on statins for the last 4years. Was placed on Crestor last dec and I had serious adverse effects like dizziness, loss of balance by taking just 2 times later placed back on Lipitor 20mg and then since 9 Sept. Lipitor was reduced to 10mg and Ezemitib 10mg was added. Now I have severe joint and muscle pain with mood swings which I can't explain. How often should liver function tests be taken especially when I have cholecystectomy done? What other options are there to reduce high LDL? With no family history of diabetes I now have high levels of HBA1C 6.5-7.2 thanks to statins. Can anyone reading this reply me? I will be very thankful. Take care all Statin users."

1 / 10
Was this helpful?YesNo
17 Report
  • Barbara
  • Taken for 1 to 6 months
  • August 2, 2021

For High Cholesterol "Extreme weakness after taking it 2 months. Then extreme hunger but unable to eat much. After stopping for 7 days, all symptoms stopped. PA said it could not be causing my symptoms because they did not appear at first! I stopped any way and after 7 days I am almost OK."

1 / 10
Was this helpful?YesNo
18 Report
  • Rick
  • Taken for 1 to 6 months
  • July 27, 2019

For High Cholesterol "I am on Ezetimibe 10 mg together with Simvastatin 20 mg for four weeks. In the mean time I stopped Fenofibrate 134 mg . It seems effective to reduce LDL-Cholesterol by 25%, total-Cholesterol by 30%. Don't know why my Trig level was cut in half from 200 to ~100. So far, don't have much side effect, but will watch in the next 3 months."

6 / 10
Was this helpful?YesNo
27 Report
  • Hels
  • Taken for less than 1 month
  • September 20, 2020

For High Cholesterol, Familial Heterozygous "Hey guys. I'm 26 years old, have severe familial hypercholesterolemia. Was on ezetimibe for only 4 days in addition to crestor 40mg. Urine became brown, had horrible fatigue and pain in my legs and feet, plus blocked nose. Have stopped taking it even though the benefit of this drug (in addition to statins) apparently outweighs the importance of my quality of life. Also dark urine suggests liver or kidney problems and I could tell the small amount of symptoms I had was only getting worse by the day. Will continue to search for an answer to my problem."

1 / 10
Was this helpful?YesNo
21 Report
  • Dennis...
  • Taken for 6 months to 1 year
  • October 9, 2016

For High Cholesterol "I was reading this blog with interest. I'm a Canadian . You are being ripped off in the US I am sorry to say. I am on 5mg of Crestor and 10mg of ezetimibe and I do not have insurance. In Canada our social health insurance pays for the doctor but not prescriptions unless you are a senior. The cost of these two drugs together is just under $20.00 per month. Yes, not $200.00 but $20.00 I suggest you vote to put pressure on the drug manufacturers to reduce their pricing structures. And btw, I have tolerated both with no side effects and my Cholesterol numbers for total are very low. My Cardiologist is happy and so am I."

10 / 10
Was this helpful?YesNo
36 Report
  • JGB-UK
  • June 18, 2017

For High Cholesterol, Familial Heterozygous "I have beeen on medicine for Familial Heterozygous High cholesterol for 15 years, Rosuvastatin half the max dose 20mg cut total cholesterol from 9.9 uk measuring system to 5.2, with no noticeable side effects. Ezetimibe reduced this by 0.6 to 4.6 monitored quarterly, side effects first diarrhoea got worse and next resembled irritable bowel symptoms and then became like having severe gastroenteritis once a fortnight with in the last 3 days worsening nausea and delayed stomach emptying for up to 24 hours followed by 2 days of extremely frequent and exhausting vomiting and diarrhoea until only clear fluid was expelled followed by 3 days recovery starting a new cycle. I endured this for 18 months with various -ve tests. Stopping ezetimibe cured these side effects completely."

4 / 10
Was this helpful?YesNo
33 Report
  • Steve
  • Taken for 1 to 6 months
  • March 10, 2021

For High Cholesterol "Sore shoulders, and neck pain. Taking this with a statin and I stopped the ezetimibe after two months. It has been two weeks off the drug and still sore, although not as bad, read that it can take up to two months for your muscles to heal."

1 / 10
Was this helpful?YesNo
18 Report
  • Lilypad
  • Taken for 2 to 5 years
  • April 29, 2019

For High Cholesterol "After having a TIA ( transient ischemic attack ) I was put on avastatin which works well. Now I've been given ezetimibe to go with it and the pain in my legs hurt. Every night I'm tired with headaches all the time. Thinking of dropping it. PS I have swollen ankles too"

4 / 10
Was this helpful?YesNo
25 Report
  • Cranky
  • Taken for less than 1 month
  • June 6, 2018

For High Cholesterol, Familial Heterozygous "After taking this drug for a week l experienced severe joint and muscle pain, stomach pain and headaches. Disappointing as l am unable to take statins for the same reason. Will just have to contend with high cholesterol."

Was this helpful?YesNo
27 Report
  • Ezzetr
  • March 25, 2017

Zetia (ezetimibe) "Was notified recently that the expensive drug Zetia now has a generic version called Ezetimibe however Zetia is a tier 3 drug and Ezetimibe is a tier 4 drug which means I will be paying even more than before since my plan will no longer carry Zetia after June 1,2017. Unbelievable!!"

5 / 10
Was this helpful?YesNo
31 Report
  • Michele
  • Taken for 6 months to 1 year
  • December 4, 2018

For High Cholesterol "I wasn’t sure if I could stay on Zetia at first because my blood pressure was lower than usual (78/56) and I had shortness of breath with extreme fatigue. I secretly took only half a pill and half of my blood pressure medication for a while (not recommended) Almost a month later, everything levelled out and I’m now taking a full dose of both meds with none of the problems listed. I had a lipid panel at the 4 month mark and my values were all normal and my LDL dropped 28 points. Best of all, recent lab work shows my liver enzymes as normal and this was the first medication that didn’t elevate them into the triple digits. I have a bit of back pain along the spine but nothing major. I’m not sure if it’s the Zetia or just me. Unless it gets unbearable, I’m gonna stay the course. $30 for the generic 90 day supply with insurance. Very pleased so far."

10 / 10
Was this helpful?YesNo
25 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.