Praluent User Reviews & Ratings (Page 4)

• Nagi
• Taken for 6 months to 1 year
• October 16, 2016

For High Cholesterol "Praluent was working great for the past 9 months without any side effects but during the last 3 weeks I started to have the symptoms of arthritis that is some pain in the joints. It improves some when I walk. I hope these symptoms will not further increase. Will update you in another 2-3 weeks."

• Frmrb...
• July 17, 2016

For High Cholesterol, Familial Homozygous "After one injection I experienced swelling of hands and feet. My blood pressure elevated by more than 50 #. Praulent researchers said I had an autoimmune reaction and that it all would pass as the Praulent left my system. After 8 months I still have the High blood pressure. I am currently being checked for Vasculitis as the result of my autoimmune reaction."

• Lilyr...
• January 26, 2017

For High Cholesterol, Familial Heterozygous "Injected Praluent 3 weeks ago. I am 74 yr old female, generally very healthy and active with familial cholesterol( not tolerant of statins etc). I had cold symptoms and a mild sore throat two days after the injection. Injected again 1 week ago, completely floored this week, with sickness and diahrrea the following day, stayed in bed that day, the following day and every morning this week as I am so tired ( injected on a Sunday, it is now Thursday). Still have a very red, sore and swollen throat and the symptoms of a heavy cold. I rarely have colds or sore throats or sickness etc. I shall not be continuing with medicine"

• debbie
• Taken for 1 to 2 years
• December 12, 2022

For High Cholesterol, Familial Heterozygous "It is now some time since I gave feedback on the Praluent. I became extremely ill and discontinued it off my own bat because we were under lockdown and could get any help. Although the episodes finished I am, nevertheless, still struggling with the effects and am beginning to believe that I shall never go back to who I was before Praluent. The consultant, reluctantly, admitted that there were 'issues' with the product but I don't see that it has been taken off the market. Where can I go for help? Do we put up with being treated like guinea pigs and then abandoned when things go wrong?"

• Peter...
• February 1, 2020

For High Cholesterol, Familial Heterozygous "I’m a 55 yr old male with familial Hypercholesteremia. I take zeros, Crestor and Praluent. My numbers are awesome. HDL, LDL all fantastic. I d been on Praluent for about 6 months so about 12 doses of 150mg. I have developed several muscle and joint pain in my hips that is now spreading into my legs. I have also developed mild neuropathy in my hands. I am an avid golfer and tennis player and it is now to the point where I have had to stop playing both and ache when I walk. I am considering going off the Praluent and just accepting my fate!!!"

• uniqu...
• Taken for less than 1 month
• April 29, 2020

For High Cholesterol "Mine is the usual story. I got horrific muscle cramps, especially in my thighs, from taking even the smallest imaginable dose of a statin (5 mg per week). I just had to stop taking any statin. I tried diet alone to lower my numbers and that didn't work. I fought trying an injectable for my cholesterol/cardiovascular issues for several years until I didn't have any options left. Two weeks ago I gave myself my first Praluent injection. I'm needle phobic so imagine my surprise when I never even felt the tiny needle and had to check to make sure it was actually in my skin. Then yesterday I did my second of my two monthly injections and it was the same; over in about 5-10 seconds! This was the big hurdle for me, so if you think you can't do an injectable, try it. It's really no big deal. This drug costs me $250/month with my Blue Cross insurance. I am hoping as users go up, the price will go down. Time will tell if my cholesterol goes down."

• Anonymous
• Taken for less than 1 month
• June 8, 2023

For High Cholesterol "I took the first Praluent 150 injection and on the 3rd day after I got a terrible UTI. On day 5, I got severe body aches and muscle spasms. I’m on my second antibiotic for the UTI. I went to the doctor once and 5 days later ended up at the ER. I’m supposed to take my 2nd injection on Saturday but that won’t be happening. I’m just hoping my body gets back to normal soon. The Praluent injection was worse than Crestor or Lipitor for me."

• Doone
• Taken for less than 1 month
• August 4, 2019

For High Cholesterol "I have only been taking this medication Praluent a short time so I can't say whether it has helped reduce my cholesterol. What I don't like about this drug is that it makes me feel nauseous and I sweat profusely which is upsetting and embarrassing as I work part time at a store as a dressing room attendant or a cashier."

• Jackie
• Taken for less than 1 month
• July 30, 2019

For Cardiovascular Risk Reduction "I cannot tolerate statins so my cardiologist suggested Praluent 75 mg. every two weeks. After the first injection I began to have burning sensation and irritation on my lips and in mouth this progressed to itching on body followed by burning skin sensation on arms and legs as well. I also have muscle and joint pain and aching as well as dizziness. Both Doctor and pharmacist said to stop it because seems to be an allergic reaction. I can't comment on effectiveness because I only took one dose. Symptoms are persisting after two weeks and I hope they end soon. I am sensitive to many drugs but was hoping I could tolerate this so I am disappointed. My cholesterol is not that high usually LDL is around 100 or slightly less with no medication. So I will continue to watch my diet carefully and hope for the best."

• Bon
• Taken for 1 to 6 months
• March 25, 2023

For High Cholesterol "Been taking 150mg of Praluent for 2 months now. The first month was perfectly fine, had no problems as I inject it in my thigh areas. However, I got a big welt and itching in that area from the third injection. I changed the injection site to my other thigh for the fourth injection and had the same side effect. Showed my cardiologist when I went in for a follow-up, but they did not seem concerned as levels were down. I’m allergic to all statins and had to try something, will continue if this is all that happens I can tolerate it with anti-itch cream. I will discontinue though if more side effects appear. Will see what happens in my third month. I’m 71 years old and have had 2 stents over 21 years. My high cholesterol numbers just jumped in the last year, possibly due to age as I’m a healthy eater, and I exercise three times a week. Will update again in 2-3 months."

• mick
• Taken for 2 to 5 years
• May 12, 2020

For High Cholesterol "I started on praluent 3 years ago not long after it was first introduced in the uk , after over ten year of on off , mostly off statins , due to there almost crippling side affects this drug has been a god send my cholesterol is below recommended levels for the first time ever for two years in a row, after having stents and one heart attack i now feel for the first time in years I'm no longer waiting for another imminent episode!. side effects, a few muscle aches but nothing like the statins and only last a short while.easy to take once every two weeks"

• Anonymous
• Taken for 5 to 10 years
• January 31, 2024

For High Cholesterol "Fifteen years ago I had two stents as I was suffering from blocked arteries and terrible angina. I was only 43 years old. I took statins for years, as much as my body could stand, as I suffered from insane muscle pain to the point where I could hardly walk. Because of this, my statin use dwindled to once or twice a week. Five years ago, with my cholesterol high again, I had a minor heart attack. I was then given Praluent, and my gosh, what a savior! Cholesterol levels down to recommended levels and no side effects. I would probably say, without exaggeration, that this drug saved me!"

• biker
• Taken for 1 to 6 months
• December 23, 2022

For High Cholesterol "I have been on this for a month. Two injections so far. I am 64 years old, I exercise frequently, and have a history of cholesterol - total number under 200 however. Since taking this drug, I have been sluggish and fatigued. The fatigue comes and goes. Prior to taking this, I rode my stationary bike about 8 to 10 miles every other day. It is difficult to do what I regularly did prior to initiating this drug. Now, my exercise routine is tougher to do and I am very fatigued after riding. PSk9 inhibitors appear to have an impact on my blood pressure response to exercise. Hypotension response appears amplified (I am going for a follow-up on this). Research I have read on the PSK9's like this says, however, that the impact is "inconclusive" with respect to BP. However, I am more fatigued being on this drug. The first few days my cognitive abilities were impaired but this did improve. I also had more frequent nighttime urination. I am not taking a third Praluent injection."

• Susan
• Taken for 1 to 6 months
• May 1, 2024

For High Cholesterol "I’ve been on it since Jan 14 every 2 weeks. I did have trouble with the injector the first month, but I finally got it right and the injections are now fine. However, this last month of doses, I’m having side effects. I have a bladder infection (positive results). I’ve had a very sore throat with drainage for 2 weeks after the last dose with a very severe cough. It started to go away but is back after my last dose 1 week ago. I feel lethargy and have a bad headache. I question whether these are side effects of the med!"

• Roman
• Taken for 6 months to 1 year
• March 17, 2024

For High Cholesterol "I've been taking Praluent 75mg for 9 months. I had experienced serious back pain after the 2nd shot for at least a week. After that, there were no side effects. Most importantly, this drug lowered my blood pressure, so I didn't need to take additional medication I had been on for years! LDL showed 100 less after 2 months on it. Recently, I had to switch to Repatha due to the fact that my insurance no longer supports Praluent. I have plenty of side effects and needed to take blood pressure medication as well. Praluent is way better, even though they are saying it's the same agent."

• Meano
• October 11, 2018

For High Cholesterol "I have had two shots getting ready for my third not sure if I want to take it because I've had chills, headache nausea a lot also aching. I'm going to get my blood test tomorrow to see if it's lowered it enough for me to keep taking this cuz the side effects for me are horrible. Also my blood pressure goes from being high to drastically low."

• EdE
• Taken for 1 to 6 months
• June 6, 2018

For High Cholesterol "My total cholesterol has dropped from 268 to 125! The “all important” LDL (bad cholesterol) has been reduced from 184 to 50! Dramatic reductions in just 6 weeks on 150mg every two weeks. My HbA1c is essentially the same at 6.6 (was 6.7)...not bad. Kidney, liver- all stable and ok. No side effects at all with Praluent. Statins are toxic to my system--not just side effects, but toxic."

• Syd
• Taken for 5 to 10 years
• April 29, 2024

For High Cholesterol "I have been using Praluent consistently since 2018 (5 1/2 years) and have not experienced one side effect from this drug. My cholesterol count reduced substantially within two months and has been maintained well within acceptable levels, ongoing. I have had annual visits to the prescribing endocrinologist, complete with blood work analysis, and all measurements have been satisfactory. Prior to being prescribed Praluent, my cholesterol count was considered ultra-high, and I had to be taken off statins as they caused memory loss. Praluent has been far more effective in reducing cholesterol and has done so with no side effects."

• Coach...
• Taken for 6 months to 1 year
• September 1, 2020

For High Cholesterol, Familial Heterozygous "I was prescribed Repatha however, my Insurance forced me to take Praluent. I started on Praluent just after Christmas 2019 and continued every 2 weekly shots through August 2020. My body will not tolerate Statin drugs, so this was my only option to try and control my Cholesterol. In December of 2019, my Total cholesterol was 286 after 8 months of using Praluent my cholesterol only went down by 2 point to 284. My Triglycerides went up by 50 points, 108 in December to 158 in august. HDL (good cholesterol) went down by 3 points, 50 in December to 47 in August. Finally, my LDL went down by 9 points, 214 in December to 205 in August. In summation, Praluent did not work for me. Hopefully, I have better results on Repatha. From a side effect point of view, I would take the injection on a Thursday and by Saturday afternoon I would be bothered with a headache. Usually by Sunday night the headache would resolve, I would be fine until my next dose."

• Crono
• Taken for less than 1 month
• December 23, 2020

For High Cholesterol "Switched from repatha to praulent due to insurance. I injected first of the month. Now after 2 Er Visits and a bunch of prednisone, it's finally starting to leave my body. To recap. The next day I felt like I got hit with the flu and had no energy and felt like crap, shorty after my whole face, fingers and feet blew up and I has covered in hives, from head to toe. I'm a day done with my steroids and the hives are already coming back. Not as bad, but enough to be bothersome, especially during bed time. If you have any sensitivity to statins, I highly suggest you stay away."

• Stairs
• Taken for 6 months to 1 year
• April 29, 2019

For High Cholesterol, Familial Heterozygous "61 y.o. female with FH (familial high cholesterol ): I had pre-existing neuralgia which was somewhat manageable, I tried statins and they brought my pain levels to 10+ so no statins for me. Praluent was okay regarding neuralgia for the first few months when I was yanking out the needle at the halfway point (due to a bad reaction to Repatha in 2018...another story for another day). 8 weeks ago when I started leaving the needle in until it retracted, i.e., giving myself the full 75 mg, that's when my neuralgia started to break through intensely. Very disappointing. I hope that, going back to the half dose, even though it's very hard to estimate when to pull out the needle -- the needle is so fast, I hope to reverse the increased neuralgia. I need a full dose but it looks like I can't tolerate it. Dang! When the nerve pain increases, my good mood disappears."

• Emily
• Taken for 1 to 6 months
• June 20, 2023

For High Cholesterol, Familial Heterozygous "I have been taking 150 mg of Praluent for 2 - 3 months and began experiencing thigh pain and weakness, worsening dizziness, and worsening neck, and right knee pain. I used to walk 3 miles a day, do cardio twice a week, weights twice a week. Now my dizziness and leg weakness does not allow me to walk without holding on to the wall or using a cane. My last injection was three weeks ago but symptoms persist though not worsening. Pending Neurology and all the usual workup but I feel strongly it’s Praluent, especially after reading these reviews. Like many others here, I cannot tolerate the statins. Was on Praluent 75mg for about a year and did experience dizziness and thigh “heaviness” and muscle cramping but not to this extent."

• Ssbelts
• Taken for less than 1 month
• June 8, 2023

For High Cholesterol "I have had a CV event and have very high LDL and high LPa and cannot tolerate statins. I started on Praluent and was fine right after the injection. But the first night I woke up with a very swollen tongue and lips and an extremely dry mouth and throat. Took 1/2 Benadryl which seemed to resolve. But over the next few days, I would experience bouts of extremely high BP and flushing of my face and chest (I tend to have low BP so this was very odd). High BP and flushing seemed to occur after any exertion and followed by extreme tiredness for a few weeks and my doctor told me not to take the next dose. Additionally, I have had very unusual headaches, and odd bruising, as well as pinpoint bleeding under my skin and bleeding (large thick clots of blood) from my nose. If I got bit by an insect I would have rubbery clots of blood on my skin. All very strange, and I will be glad when this med has worked its way out of my system (about 40 days). FYI I do have a lot of sensitivity to many meds so I am not surprised."

• Lon
• Taken for 1 to 6 months
• July 20, 2018

For High Cholesterol "After 15 years on statins I could not accept Iiving with the continuous aches and pains. After three months on Praluent I feel fine, no noticeable side affects, no problem with injections. Cholesterol numbers reduced dramatically."

• Paul
• Taken for 5 to 10 years
• March 15, 2023

For High Cholesterol "My family has a genetic history of high cholesterol. I've been using Praluent since it came out after the clinical trials. We arranged a cath lab examination two years after I started taking the Praluent, and everything looked normal around the heart, with no calcium buildup other than one little speck. I've never had a stroke or heart attack. My cholesterol levels are in the normal range but were high when I was younger. Statins had too many side effects, and I stopped using them. The side effects are minimal to date. I take two injections twice a month, 150 mg. each."