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Sacubitril use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on Feb 27, 2024.

Drugs containing Sacubitril: Entresto, Entresto Sprinkle

Sacubitril Levels and Effects while Breastfeeding

Summary of Use during Lactation

Sacubitril is available in the United States only in combination with valsartan. Because no information is available on the use of sacubitril or valsartan during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Benazepril, Enalapril, Quinapril

Substance Identification

Substance Name

Sacubitril

CAS Registry Number

149709-62-6

Drug Class

  • Breast Feeding
  • Lactation
  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents
  • ACE Inhibitors
  • ACEIs

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.