Dronabinol is the synthetic form of delta-9-tetrahydrocannabinol, the major active component of cannabis. Delta-9-tetrahydrocannabinol is found in the breastmilk of mothers who use cannabis products.[1-3] Because no published information is available with dronabinol use as an antiemetic during breastfeeding, an alternate antiemetic should be used.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Bertrand KA, Hanan NJ, Honerkamp-Smith G, et al. Marijuana use by breastfeeding mothers and cannabinoid concentrations in breast milk. Pediatrics. 2018;142:e20181076. [PMC free article: PMC6317767] [PubMed: 30150212]
2.
Baker T, Datta P, Rewers-Felkins K, et al. Transfer of inhaled cannabis into human breast milk. Obstet Gynecol. 2018;131:783–8. [PubMed: 29630019]
3.
Wymore EM, Palmer C, Wang GS, et al. Persistence of Δ-9-tetrahydrocannabinol in human breast milk. JAMA Pediatr. 2021;175:632–4. [PMC free article: PMC7941249] [PubMed: 33683306]
Substance Identification
Substance Name
Dronabinol
CAS Registry Number
1972-08-3
Drug Class
Breast Feeding
Lactation
Milk, Human
Antiemetics
Cannabinoids
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