Wainua Side Effects

Generic name: eplontersen

Note: This document contains side effect information about eplontersen. Some dosage forms listed on this page may not apply to the brand name Wainua.

Applies to eplontersen: subcutaneous solution.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• vision problems--trouble seeing at night or in low lit areas (night blindness), or dry eyes.

Common side effects may include:

• eye problems;

• dry skin; or

• vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to eplontersen: subcutaneous solution.

General

The most frequently reported side effects included decreased vitamin A and vomiting.^[Ref]

Cardiovascular

Common (1% to 10%): Atrioventricular (AV) heart block

Frequency not reported: Complete AV block

AV heart block included at least 1 case of complete AV block.

Gastrointestinal

Common (1% to 10%): Vomiting

Genitourinary

Common (1% to 10%): Proteinuria

Local

Common (1% to 10%): Injection site reactions

Injection site reactions included erythema, pain, and pruritis.

Metabolic

Very common: Decreased vitamin A (15%)

Decreased vitamin A included vitamin A deficiency and decreased vitamin A.

Ocular

Common (1% to 10%): Blurred vision, cataract

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer