Vabysmo Side Effects

Generic name: faricimab

Medically reviewed by Drugs.com. Last updated on May 31, 2023.

Note: This document contains side effect information about faricimab. Some dosage forms listed on this page may not apply to the brand name Vabysmo.

Applies to faricimab: intraocular solution.

Serious side effects of Vabysmo

Along with its needed effects, faricimab (the active ingredient contained in Vabysmo) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking faricimab:

More common

Bloody eye
redness of the eye

Less common

Blurred vision
change in vision
eye pain
loss of vision
red, sore eyes
seeing floaters, veil or curtain appearing across part of vision
seeing floating dark spots or material before the eyes
tearing

Rare

Eye irritation
seeing light flashes
watering of the eyes

Incidence not known

Chest pain, discomfort, or tightness
fast heartbeat
fever
hives, itching, rash
hoarseness
irritation
joint pain, stiffness, or swelling
nausea
pain or discomfort in the arms, jaw, back, or neck
redness of the skin
stroke
sweating
swelling of the eyelids, face, lips, hands, or feet
trouble breathing
vomiting

For Healthcare Professionals

Applies to faricimab: intravitreal solution.

Cardiovascular

Common (1% to 10%): Arterial thromboembolic events (defined as nonfatal stroke, nonfatal myocardial infarction, vascular death [including deaths of unknown cause])^[Ref]

In the neovascular age-related macular degeneration studies, arterial thromboembolic events were reported in 1% of patients during the first year. In the diabetic macular edema studies, arterial thromboembolic events were reported in 2% of patients during the first year.^[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions^[Ref]

Immunologic

Very common (10% or more): Anti-drug antibodies (up to 10.4%)^[Ref]

Ocular

Very common (10% or more): Cataract (10.7%)

Common (1% to 10%): Conjunctival hemorrhage, eye pain, increased intraocular pressure, increased lacrimation, retinal pigment epithelial tear, vitreous floaters

Uncommon (0.1% to 1%): Blurred vision, corneal abrasion, conjunctival hyperemia, endophthalmitis, eye irritation, eye pruritus, iridocyclitis, iritis, ocular discomfort, ocular hyperemia, retinal tear, sensation of foreign body, uveitis, reduced visual acuity, vitreous hemorrhage, vitritis

Rare (0.01% to 0.1%): Rhegmatogenous retinal detachment, transiently reduced visual acuity^[Ref]